脉冲恒电位一步法制备聚3,4-乙烯二氧噻吩石墨烯复合材料构建无酶葡萄糖传感器  

Construction of Nonenzymatic Glucose Sensor Based on One Step Preparation of Poly (3,4-ethylenedioxythiophene) Graphene Composite Materials by Pulse Potentiostatic Method

作　　者：李敬敬 李慧 贾丽萍[1] 马荣娜[1] 贾文丽[1] 王怀生[1] 

机构地区：[1]聊城大学化学化工学院,聊城252059

出　　处：《分析化学》2017年第12期2004-2010,共7页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金项目(Nos.21375055;21427808;21405070)资助~~

摘　　要：本研究利用石墨烯(rGO)与3,4-乙烯二氧噻吩(EDOT)单体芳香环之间的π-π~*相互作用和氢键作用,采用脉冲恒电位一步法制备了聚3,4-乙烯二氧噻吩石墨烯(PEDOT-r GO)复合膜,将纳米镍(NiNPs)电沉积在此复合膜(PEDOT-r GO)表面,制备了Ni NPs/PEDOT-r GO修饰玻碳电极(Ni NPs/PEDOT-r GO/GCE),研究了此修饰电极对葡萄糖的电催化氧化性能。实验结果表明,此Ni NPs/PEDOT-r GO/GCE可以作为无酶传感器实现对葡萄糖的检测。本方法稳定性高,选择性好,线性范围宽(2μmol/L^58 mmol/L),检出限低至0.7μmol/L,可以用于对葡萄糖的快速、灵敏检测。The Poly( 3,4-ethylenedioxythiophene) graphene( PEDOT-r GO) composite film was prepared by one step pulse potentiostatic method,based on the π-π~* interaction and the polymerization reaction of hydrogen bond between the graphene( r GO) and the aromatic ring of 3,4-ethylenedioxythiophene( EDOT)monomer. Then the nickel nanoparticles( Ni NPs) were electrodeposited on composite film to obtain a composite film-modified glassy carbon electrode( Ni NPs/PEDOT-r GO/GCE). The catalytic performance of Ni NPs/PEDOT-r GO/GCE towards the oxidation of glucose was studied by electrochemical method. The experimental results showed that the Ni NPs/PEDOT-r GO/GCE could be used as a nonenzyematic sensor for detection of glucose. This method had high stability,good selectivity,wide linear range( 2 μmol/L-58 mmol/L) and low detection limit( 0.7 μmol/L),realizing the rapid and sensitive detection of glucose.

关 键 词：聚3 4-乙烯二氧噻吩 石墨烯复合材料 纳米镍 葡萄糖 无酶传感器 

分 类 号：TB33[一般工业技术—材料科学与工程] TP212[自动化与计算机技术—检测技术与自动化装置]