三棱化学成分及药理作用研究进展  

Research progress on chemical constituents and pharmacological activities of Sparganium stoloniferum

作　　者：冯娅茹 张文婷[1] 李二文[1] 刘雯雪 梅雪 罗隽 杨冉冉 马志强[1] 林瑞超[1] 

机构地区：[1]北京中医药大学中药品质评价北京市重点实验室,北京100102

出　　处：《中草药》2017年第22期4804-4818,共15页Chinese Traditional and Herbal Drugs

基　　金：国家重大新药创制项目(2014ZX09304307001)

摘　　要：三棱Sparganium stoloniferum为临床常用药材,近年来关注度一直较高。三棱中主要含挥发油、苯丙素类、黄酮类等化学成分,具有抗血栓、抗炎、镇痛、抗肿瘤等药理作用,其临床常用于治疗子宫内膜异位症、慢性萎缩性胃炎等。从本草考证、化学成分、药理作用3个方面对三棱近10年的研究进展进行综述,以期能为今后三棱的开发和利用提供参考。Sparganium stoloniferum is widely used in traditional Chinese medicines. It has been reported to exhibit therapeutic effects on thrombus, solid tumor, endometriosis and so on. It is usually used to treat endometriosis and chronic atrophic gastritis, while its underlying mechanisms are poorly delineated. According to vast information fromLiteratures in the last decade, the research on origin of medica, chemical compositions and pharmacological actions were summarized, in hopes of offering more clues for further research as well as clinical application of S. stoloniferum.

关 键 词：三棱 本草考证 挥发油 苯丙素类 黄酮类 抗血栓 抗炎镇痛活性 抗肿瘤活性 

分 类 号：R282.74[医药卫生—中药学]