医院内革兰阳性球菌感染的调查及耐药分析  

Clinical analysis of resistance and survey of gram rositive cocci infection in hospital

作　　者：褚云卓[1] 王倩[1] 年华[1] 丁丽萍[1] 

机构地区：[1]中国医科大学第一临床学院检验科,辽宁沈阳110001

出　　处：《中国实验诊断学》2002年第4期210-212,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的　了解医院内感染的革兰阳性球菌的分布及耐药情况 ,指导临床医生合理应用抗生素 ,防止耐药菌株的爆发流行。方法　药敏试验采用K -B纸片扩散法 ,结果用WHONET5软件进行统计学分析。结果　共分离革兰阳性球菌 110 3株 ,占所有分离菌株的百分比为 2 5 % ,主要是肠球菌和葡萄球菌 ,肠球菌对所监测的抗生素均有不同程度的耐药 ,金黄色葡萄球菌除未发现万古霉素耐药外对其他监测的抗生素均有不同程度的耐药。结论　革兰阳性球菌在医院感染中仍占有重要地位 ,MRS和VRE的感染较常见 ,对革兰阳性球菌进行规范的耐药监测工作是十分必要和重要的。Objective To understand distribution and resistant of gram positive cocci in hospital infection, and to direct clinical doctor use antibiotics with reason, and to prevent resistant strains outbreak and prevalence. Methods Antibiotic susceptivity test was done by Kirby-Bauer method. The result was analyzed by WHONET5 software.Result Gram positive cocci were 25% in hospital infection, which enterococci and staphylococci were major. Enterococcus expressed resistance to antibiotics to some degree. Stapylococcus aureus expressed resistance to antibiotics to some degree except for vancomycin.Conclusion Gram positive cocci were still important in hospital infection. MRS and VRE was frequent appear. It is quite necessary and important that we normatively monitor resistance of gram positive cocci.

关 键 词：革兰阳性球菌 院内感染 肠球菌 葡萄球菌 耐药性 药敏试验 

分 类 号：R446.5[医药卫生—诊断学]