干细胞对糖尿病足的治疗研究进展  

Actuality of stem cell therapy on diabetic foot

作　　者：高弘烨 黄平平[1] 

机构地区：[1]中国医学科学院北京协和医学院血液学研究所,天津300020

出　　处：《中华细胞与干细胞杂志（电子版）》2017年第5期309-312,共4页Chinese Journal of Cell and Stem Cell（Electronic Edition）

基　　金：中国医学科学院医学与健康科技创新工程(2017-I2M-1-016);天津市科技计划项目(13ZCZDSY02200)

摘　　要：糖尿病足患者大部分伴有下肢缺血,而缺血是导致糖尿病足溃疡不愈和截肢的最主要原因。传统的治疗方法并不能很好的降低其截肢率,糖尿病足溃疡已经成为世界范围内临床医学的难题。因此,深入研究糖尿病足的发病机制及下肢血管病变特点,探索新的治疗策略及推广应用,具有重要的社会意义。干细胞已经广泛应用于多个领域,其分泌细胞因子促进新生血管生成等机制为治疗糖尿病足提供了可能。本文就近年来干细胞治疗糖尿病足的研究进展作一综述。The patients with diabetic foot were mostly associated with lower extremity ischemia. It is the most important reason leading to diabetic foot ulcer, which is hard to be cured so as to been amputated. Traditional therapies could not reduce its high level amputation rate, which has been the clinical problem worldwide. Therefore, it is of important social significance to further explore the pathogenesis of diabetic foot, lower extremity vascular disease characteristics and new remedies strategies, and to promote the application. Stem cells has been already widely used in many fields. The functions such as the secretion cytokines can promote the angiogenesis and make the remedies on diabetic foot possible. This paper summarizes the research progress on actuality of stem cell therapy on diabetic foot further.

关 键 词：糖尿病足 截肢 干细胞移植 

分 类 号：R587.2[医药卫生—内分泌]