超声技术在评估冠心病患者外周血管与冠状动脉粥样硬化相关性应用  

Evaluation of ultrasonography in the correlation between peripheral blood vessels and coronary atherosclerosis in patients with coronary heart disease

作　　者：徐洋洋[1] 王效增[1] 周微微[1] 刘楠楠[1] 焦晓芳 曹剑峰 李贵申[1] 王莲玉 邢小飞[1] 

机构地区：[1]沈阳军区总医院心血管内科,辽宁沈阳110016

出　　处：《临床军医杂志》2017年第11期1126-1129,共4页Clinical Journal of Medical Officers

基　　金：辽宁省自然科学基金(20092089)

摘　　要：目的利用超声技术探讨冠心病(CHD)患者外周血管与冠状动脉粥样硬化之间的相关性。方法选取沈阳军区总医院2016年1—4月临床上确诊为CHD的患者52例(CHD组),同时,选取同期健康体检者30例(健康组),对两组研究对象均进行外周血管的超声检查。CHD组依据冠脉造影检查(CAG)结果显示累及的冠脉支数又分为3个亚组,其中,单支组17例,双支组16例,三支组19例。测量的主要内容主要有各段血管的管腔内径、内-中膜厚度(IMT)、收缩期血流速度(PSV)、阻力指数(RI)、搏动指数(PI)、斑块的大小等指标,并估算斑块的Crouse积分。分析相关数据,探讨外周血管病变与冠状动脉疾病之间的相关性。结果与健康组比较,CHD组患者的颈部血管内径增加,下肢血管的内径减小,且随着冠脉受累支数的增加差异更显著;CHD组IMT、粥样斑块检出率以及斑块的Crouse积分均比健康组有不同程度的增加。简单相关分析结果表明,IMT、斑块的Crouse积分均与冠脉病变的Gensini评分有关,其中,颈动脉IMT、股动脉IMT、颈动脉斑块的Crouse积分、股动脉斑块的Crouse积分的相关系数分别为0.78、0.69、0.53、0.58,均为正相关。结论外周血管与冠状动脉粥样硬化之间有一定相关性,且随着外周血管粥样硬化程度的加重,冠状动脉粥样硬化程度也随之加重。外周动脉的超声检查作为一种简便、有效、可重复性好的检查手段,可以为CHD的早期筛查、预防提供重要信息。Objective To investigate the application of ultrasound in correlation between peripheral blood vessels and coronary atherosclerosis in patients with coronary heart disease.Methods A retrospective study was performed on 52 patients with coronary heart disease（CHD） from January to April 2016.Patients with CHD were in the CHD group,at the same time,30 volunteers were divided into the healthy group.Ultrasonography was performed on peripheral vascular between the two groups.Coronary angiography（CAG） showed that according to the number of coronary artery,patients in the CHD group were divided into three subgroups,including 17 cases of single count group,16 cases of double counts group and 19 cases of three counts group.The endovascular diameter of the blood vessels,inner-medium film thickness（IMT）,systolic blood flow velocity（PSV）,resistance index（RI）,pulsatility index（PI）,size of plaque and other indicators of the vascular were measured and the patch of Crouse score was estimated.Statistical analysis of the measured data was to analyze the correlation between peripheral vascular and coronary artery disease.Results Compared with the healthy group,the diameter of the neck of the CHD group increased,the diameter of the lower limb blood vessels reduced,and with the increase of the number of coronary artery involvement,the differences were more significant;in the CHD group,the detection rate of IMT,atherosclerotic plaque and Crouse score of plaque were increased in different degrees compared with those of the healthy group.The results of simple correlation analysis showed that the Crouse scores of IMT and plaque were related to the Gensini score of coronary artery lesion,including the IMT of the carotid artery,the Crout of the femoral artery,the Crouse score of the carotid plaque,and the Crouse integral of the femoral plaque were positively correlated,and were 0.78,0.69,0.53,0.58,respectively.Conclusion Peripheral blood vessels and coronary atherosclerosis has a certain correlation,and with the degr

关 键 词：超声 冠心病 外周血管 内-中膜厚度 斑块 

分 类 号：R541.4[医药卫生—心血管疾病]