儿童睡眠呼吸障碍应用个体化治疗的价值分析  

Value analysis of individual therapy for the treatment of sleep disordered breathing in children

作　　者：于秋红 苏轶 黄秀娟 齐君君 李建东 

机构地区：[1]山东省东营市人民医院耳鼻咽喉科,257091

出　　处：《中国实用医药》2017年第32期11-14,共4页China Practical Medicine

摘　　要：目的比较个体化治疗和单纯行手术治疗儿童睡眠呼吸障碍[阻塞性睡眠呼吸暂停低通气综合征(OSAHS)]的疗效。方法 232例OSAHS患儿,依据治疗方法不同分为观察组(126例)与对照组(106例)。观察组采用个体化治疗,即采用非手术治疗和手术治疗的结合方式,对照组单纯行手术治疗。观察两组疗效,记录患儿的体质量指数(BMI)、呼吸暂停低通气指数(AHI)、平均动脉血氧饱和度(MSaO_2)、最低动脉血氧饱和度(LSaO_2)、血氧饱和度90%时间占监测总时间的百分比(TS90%)。结果观察组治愈35例,显效52例,有效34例,无效5例;对照组治愈12例,显效36例,有效53例,无效5例;观察组总体疗效优于对照组,差异具有统计学意义(P<0.05)。观察组治疗后3个月BMI、AHI、TS90%均低于治疗前,MSaO_2、LSaO_2均高于治疗前,差异均具有统计学意义(P<0.05)。对照组治疗后3个月AHI、TS90%均低于治疗前,LSaO_2均高于治疗前,差异均具有统计学意义(P<0.05)。治疗后3个月观察组BMI、AHI、TS90%较对照组降低更明显,MSaO_2、LSaO_2较对照组升高更明显,差异均具有统计学意义(P<0.05)。结论个体化治疗可以明显提高OSAHS患儿的治疗效果。Objective To compare the efficacy of individual therapy and simple surgical treatment for sleep disordered breathing [obstructive sleep apnea hypopnea syndrome（OSAHS）] in children. Methods A total of 232 OSAHS children were divided by different treatment methods into observation group（126 cases） and control group（106 cases）. The observation group received individual therapy, that is, combination of non-surgical treatment and surgical treatment. The control group received simple surgical treatment. Efficacy in two groups was observed, and record were made on body mass index（BMI）, apnea hypopnea index（AHI）, mean arterial oxygen saturation（MSaO2）, lowest arterial oxygen saturation（LSaO2）, percent of the total recorded time spent below 90% oxygensaturation level（TS90%） between two groups. Results The observation group had 35 cured cases, 52 excellent cases, 34 effective cases and 5 ineffective cases, while the control group had 12 cured cases, 36 excellent cases, 53 effective cases and 5 ineffective cases. The observation group had better total efficacy than the control group, and the difference was statistically significant（P〈0.05）. After 3 months of treatment, the observation group had lower BMI, AHI and TS90% than before treatment, and higher MSaO2 and LSaO2 than before treatment, and their difference was statistically significant（P〈0.05）. After 3 months of treatment, the control group had lower AHI and TS90% than before treatment, and higher LSaO2 than before treatment, and their difference was statistically significant（P〈0.05）. After 3 months of treatment, the observation group had obviously lower BMI, AHI and TS90% than the control group, and obviously higher MSaO2 and LSaO2 than the control group, and their difference was statistically significant（P〈0.05）. Conclusion Individual therapy can obviously improve the treatment effect of OSAHS children.

关 键 词：儿童睡眠呼吸障碍 个体化治疗 疗效 

分 类 号：R766[医药卫生—耳鼻咽喉科]