血清孕酮和β-HCG检测在异位妊娠早期诊断中的应用价值  

Value of Serum Progesterone and β-Human Chorionic Gonadotrophin Detection in Early Diagnosis of Ectopic Pregnancy

作　　者：蒋敏[1] 吴瑞珊[1] 孟艳辉[1] 何丽萍[1] 梁惠民[1] 苗竹林[2] 

机构地区：[1]广东省计划生育科学技术研究所检验科,广州510600 [2]广东省计划生育科学技术研究所内分泌免疫科,广州510600

出　　处：《实用临床医学（江西）》2017年第10期34-35,67,共3页Practical Clinical Medicine

摘　　要：目的分析血清孕酮和β-HCG检测在于异位妊娠早期诊断中的有效性。方法将2015年2月至2016年10月间接收的37例异位妊娠孕妇和35例正常孕妇分别作为观察组和对照组,2组均接受血清孕酮及β-HCG检测,并对检测后的4~6周2组妇女的血清孕酮及β-HCG的变化进行比较。结果观察组第4周,β-HCG与对照组比较差异无统计学意义(P>0.05),孕酮则明显低于对照组(P<0.05);第5、6周观察组β-HCG、孕酮均显著低于同期对照组(P<0.05)。血清孕酮及β-HCG联合检测的符合率高于β-HCG单独检测,差异有统计学意义(P<0.05)。结论血清孕酮和β-HCG联合检测能够有效缩短异位妊娠的确诊时间,并降低误诊和漏诊的发生率。Objective To analyze the effectiveness of serum progesterone andβ-human chorionic gonadotrophin(β-HCG)detection in early diagnosis of ectopic pregnancy.Methods Serum levels of progesterone andβ-HCG were detected in 37 patients with ectopic pregnancy(observation group)and 35 normal pregnant women(control group)between February 2015 and October 2016.Furthermore,serum progesterone andβ-HCG levels were compared at 4-6 weeks after the first detection.Results At week 4,there was no significant difference inβ-HCG level between the two groups(P>0.05),but progesterone level in observation group was lower than that in control group(P<0.05).At weeks 5 and 6,both progesterone andβ-HCG levels in observation group were lower than those in control group(P<0.05).Compared with singleβ-HCG detection,the combined progesterone andβ-HCG determination increased the coincidence rate(P<0.05).Conclusion The combined detection of progesterone andβ-HCG can effectively shorten the diagnosis time and reduce the incidence of misdiagnosis and missed diagnosis in patients with ectopic pregnancy.

关 键 词：血清孕酮 Β-HCG 异位妊娠 确诊时间 检测符合率 

分 类 号：R714.22[医药卫生—妇产科学]