451例STD患者的生殖支原体感染  

Mycoplasma genitalium infection in 451 patients with sexually transmitted diseases

作　　者：王荷英[1] 施美琴[1] 叶顺章[1] 赖伟红[1] 张传福[1] 姜文华[1] 薛华忠[1] 王红春[1] 

机构地区：[1]中国医学科学院中国协和医科大学皮肤病研究所

出　　处：《临床皮肤科杂志》2002年第9期543-544,共2页Journal of Clinical Dermatology

摘　　要：为了解性传播疾病(STD)患者中感染生殖支原体(Mg)的状况及其临床意义,在本所的STD门诊部收集451例患者的尿道(宫颈)分泌物作了Mg检测。标本接种于改良的SP-4培养基作Mg分离培养,并同时用聚合酶链反应(PCR)进行Mg检测,以PCR结果作为最终判断依据。患者中69例非淋病性尿道炎(NGU)病人还作了咽部拭子的Mg检测。结果证明,Mg阳性患者有67例(14.9%),其中NGU59例(20.6%),其他STD仅8例(4.9%),二者差异有统计学显著性(P<0.0001),表明Mg感染与NGU发生关系密切。尿道(宫颈)分泌物及咽拭子同时检测Mg的69例NGU病人中,7例在二部位均检出Mg,提示有口淫的可能性。To investigate the prevalence and implication of Mycoplasma genitalium(Mg )infection in patients with sexually transmitted diseases(STD),the occurrence of the Mg was examined in the genital specimens collected from451patients with STD in the National Center of STD Control.These specimens were inoculated in modified SP-4media to isolate Mg,and the presence of the Mg was also determined by polymerase chain reaction(PCR).In addition,Mg was examined in pharyngeal samples from69patients with nongonococcal urethritis(NGU).Mg was detected positive in14.9%(67/451)of all patients.Mg was detected positive in20.6%(59/287)of patients with NGU and4.9%(8/164)of patients with other STD(P<0.0001).Mg was detected positive in both genital and pharyngeal samples in10.1%(7/69)of patients with NGU.It indicated that genital Mg infection may be associated with oral-genital sex.

关 键 词：生殖支原体 性传播疾病 非淋菌性尿道炎 临床意义 

分 类 号：R759[医药卫生—皮肤病学与性病学]