西藏人体维生素D测量  

Human Vitamin D Measurement in Tibet

作　　者：措加旺姆[1] 段杰[1] 诺桑[1] 卓玛次仁[2] Li Wei Ma Johan Moan 

机构地区：[1]西藏大学太阳紫外线实验室,西藏拉萨850012 [2]西藏自治区人民医院干部保健门诊,西藏拉萨850000 [3]Department of Radiation Biology,Institute for Cancer Research,Oslo University Hospital

出　　处：《药物生物技术》2017年第5期414-417,共4页Pharmaceutical Biotechnology

基　　金：‘西藏大学珠峰学者培养计划’和挪威西藏大学合作网项目资助项目

摘　　要：为了解西藏自治区当地居民维生素D的状况,并探究影响维生素D含量的可能原因,于2008~2009年连续6次对西藏日喀则尼仓村16名农民(男性7人,女性9人)采集血样,共计81份血样;于2012,2013年两次在西藏拉萨、定日、那曲、日喀则4个地区各选取15~50名居民采集血样,最终获得290份血样。其中126份来源于男性,164份来源于女性。血样经自治区人民医院专业医师处理后提取血清后采用放射免疫法测定血清25(OH)D含量。经分析,西藏地区平均血清25(OH)D含量为12.25 ng/m L。男性的血清25(OH)D含量为(12.8±4.9)ng/m L,女性平均为(11.9±5.3)ng/m L。根据中国老年学学会骨质疏松委员会标准,仅10.4%的男性和4.2%的女性维生素D含量达到足够状态(P<0.05)。青年人的血清25(OH)D水平要高出中老年人20%。夏季的血清25(OH)D水平要高于冬季约30%。不同职业的人群血清25(OH)D水平具有差异,牧民、教师和学生的均高于农民。总之,西藏自治区平均维生素D含量处于不足状态;通过观察发现,这与当地居民的衣着方式、肤色和饮食习惯有很大的关系。另外,不同季节、年龄、性别、地区人体血清25(OH)D含量不一样。其中原因值得我们去反思和探究。To preliminarily evaluate the status of Vitamin D in Tibetan residents and explore the possible factors affecting the content of vitamin D,blood samples of 16 farmers（7 men and 9 women） who live in Nicang village,Shigatse and Tibet were collected for six times during 2008 and 2009,a total of 81 blood samples were taken. Blood samples of 15-50 residents in Lhasa,Tingri,Naqu and Shigatse were collected twice during 2012 and 2013,290 blood samples were eventually obtained. Of these,126 came from men and 164 from women. The blood sample was processed by the professional doctor of the people＇ s Hospital of autonomous region to extract the serum. The contents of serum 25（OH） D was measured by radioimmunoassay. After analyzing,the average concentration of serum 25（OH） D in Tibetans is 12. 25 ng/m L. The concentration of serum 25（OH） D was（12. 8 ± 4. 9） ng/m L for males and（11. 9 ± 5. 3） ng/m L for females. According to the standard issued by the Osteoporosis Committee for the Gerontological Society of China,only 10. 4% in males and 4. 2% in females among the blood samples had sufficient Vitamin D（P 0. 05）. The concentration of serum 25（OH） D for the youth is 20% higher than the middle and the old. The concentration of serum 25（OH） D in summer is about 30% higher than was in winter. There are significant differences in serum 25（OH） D levels among different occupations. The concentration of serum 25（OH） D in herdsmen,teachers and students was higher than in farmers. In a word,the average concentration of serum 25（OH） D in Tibetans is insufficient,which has a lot to do with the way people dress,their skin color,and their eating habits according to observation. The concentration of serum 25（OH） D is different in terms of different seasons,age,sex and regions. The reasons behind the problem are worth our reflection and exploration.

关 键 词：西藏 人体维生素D 太阳紫外线 农民 牧民 肤色 饮食习惯 

分 类 号：Q565[生物学—生物化学]