透明质酸钠凝胶联合明胶海绵预防宫腔粘连的研究  

Study on Sodium Hyaluronate Gel Combined with Gelatin Sponge in Prevention of Intrauterine Adhesions

作　　者：吴言英[1] 王敏[1] 

机构地区：[1]茂名市妇幼保健院,广东茂名525000

出　　处：《黑龙江医药》2017年第6期1214-1216,共3页Heilongjiang Medicine journal

基　　金：茂名市科学技术局2015年计划项目(项目编号:20150333)

摘　　要：目的:探索透明质酸钠凝胶联合明胶海绵预防宫腔粘连的临床应用价值。方法:将2012年1月至2017年5月收治的行宫腔镜电切术后患者250例分为两组,A组行透明质酸钠凝胶联合明胶海绵治疗(160例),B组为空白对照组(90例),分析对比其宫腔粘连发生率及临床不良反应。结果:A组在1、3个月宫腔粘连发生率均显著低于B组(P<0.05),各种不良反应发生率显著低于B组(P<0.05)。结论:采用透明质酸钠凝胶联合明胶海绵填塞宫腔和宫颈管是预防宫腔镜电切术后宫腔粘连安全、有效的措施,值得进一步推广。Objective: To investigate the clinical value of sodium hyaluronate gel combined with gelatin sponge in the prevention of intrauterine adhesions. Methods: from January 2012 to May 2017 were underwent hysteroscopic surgery patients 250 cases were divided into two groups, A group received sodium hyaluronate gel combined with gelatin sponge in the treatment(160 cases), B group(90 cases), comparison of the incidence of intrauterine adhesions and clinical adverse reaction. Results: the incidence of cavity adhesion in group 1 and 3 in A was significantly lower than that in group B(P<0.05), and the incidence of adverse reactions was significantly lower than that in group B(P<0.05). Conclusion: the use of sodium hyaluronate gel combined with gelatin sponge to fill the uterine cavity and cervical canal is a safe and effective way to prevent intrauterine adhesions after hysteroscopic resection, and is worthy of further promotion.

关 键 词：透明质酸钠凝胶 明胶海绵 宫腔黏连 

分 类 号：R711.74[医药卫生—妇产科学]