心理干预对乳腺癌根治术后乳房缺失患者生活质量影响的meta分析  

meta-analysis of effect of psychological intervention on quality of life in breast deletion patients with breast cancer after radical mastectomy

作　　者：潘梦婷[1] 孟爱凤[2] 智晓旭[2] 邾萍[2] 胡月[1] 姚芳[1] 薛莲[1] 朱娟芳[2] 

机构地区：[1]南京中医药大学护理学院,南京市210009 [2]江苏省肿瘤医院

出　　处：《护理实践与研究》2017年第22期1-6,共6页Nursing Practice and Research

基　　金：江苏省卫生计生委科研课题(N201601);江苏省卫生计生委预防医学科研课题(Y2015063)

摘　　要：目的:通过meta分析来探讨心理干预能否对乳腺癌根治术后乳房缺失的患者生活质量产生影响。方法:计算机检索CNKI,万方,维普,CBMdisc,Cochrane Library,JBI Library,Pub Med,Web of science,MEDLINE,Embase等中英文数据库,检索关于对于乳腺癌根治术后进行心理干预的随机对照试验(RCT),检索时间是至建库以来至2016年5月。按照Cochrane系统评价方法,由2名评价者单独进行文献的筛选,纳入最终文献后进行质量评价、信息提取,采用RevMan 5.3对数据进行分析。结果:最终纳入13个RCT研究,meta分析结果显示,试验组与对照组生活质量相比,自行设计量表MD=8.76,95%CI(6.60,10.93),P<0.00001,生活质量核心问卷MD=5.56,95%CI(2.71,8.41),P=0.0001,癌症康复评价简表MD=-4.81,95%CI(-7.24,-2.39),P=0.0001,结果均具有统计学意义;使用单个量表描述性分析,结果具有统计学意义。结论:在现有的研究证据下,心理干预能够改善乳腺癌根治术后乳房缺失患者的生活质量,但是还存在阴性结果,并且纳入的研究质量并不高,还需进一步证实可靠性。Objective： To explore the effect of psychological intervention on the quality of life in breast deletion patients with breast cancer after radical mastectomy by meta-analysis. Methods： On-line retrieval was applied to databases in Chinese and English including CNKI,Wanfang,VIP,CBMdisc,Cochrane Library,JBI Library,Pub Med,Web of science,MEDLINE,Embase and so on for randomized controlled trials（ RCT） for psychological intervention after radical mastectomy for breast cancer. The retrieval time was from the establishment of the databases to May 2016. According to the Cochrane system evaluation,2 reviewers independently screened the literature and included the qualified in the final literature for quality evaluation and information extraction. RevMan 5. 3 was adopted for data analysis. Results： A total of 13 RCT studies were included finally. The meta-analysis showed that compared with the control group,self-designed scale MD = 8. 76,95% CI（ 6. 60,10. 93）,P 0. 00001,quality of life core questionnaire MD = 5. 56,95% CI（ 2. 71,8.41）,P = 0. 0001,cancer rehabilitation evaluation table MD =-4. 81,95% CI（-7. 24,-2. 39）,P = 0. 0001,in the experimental group,and the results were statistically significant. A single scale was adopted for descriptive analysis,and the results were statistically significant. Conclusion： Under the existing research evidence,psychological intervention can improve the quality of life of breast deletion patients with breast cancer after mastectomy,but there are negative results,and the quality of the research is not high,therefore,the reliability of psychological intervention requires further confirmation.

关 键 词：心理干预 乳腺癌根治术 生活质量 随机对照试验 META分析 

分 类 号：R473.73[医药卫生—护理学]