猪源沙门菌流行病学调查与耐药性分析  

Prevalence andantimicrobial susceptibility of Salmonella isolates from pigs in China

作　　者：焦连国[1] 杨贵燕 苏金辉 朱要宏[1] 赵亚荣 王安如 王九峰[1] 

机构地区：[1]中国农业大学动物医学院,北京海淀100193 [2]北京大北农科技集团股份有限公司动物医学研究中心,北京海淀100195 [3]饲用微生物工程国家重点实验室,北京海淀100192

出　　处：《中国兽医杂志》2017年第10期17-19,23,I0002,共5页Chinese Journal of Veterinary Medicine

基　　金：国家重点研发计划项目(2017YFD0502200);公益性行业(农业)科研专项(201403054);国家自然科学基金(21026089)

摘　　要：沙门菌作为常见的食源性病原菌之一,同时是引起断奶仔猪腹泻的重要病原菌之一,我国每年因沙门菌感染所引起的经济损失严重。沙门菌感染通常会导致猪副伤寒,主要特征是严重的系统性疾病,并且可能会导致肠炎或腹泻性疾病。本研究通过收集全国范围内仔猪腹泻样品,对沙门菌进行分离鉴定,了解规模化猪场沙门菌流行情况,同时对沙门菌抗生素敏感性进行分析。从我国16个省份,84个猪场,571份样品中分离得到的128株沙门菌中,发现最常见的血清型是鼠伤寒沙门菌,其次是德尔卑沙门菌、伦敦沙门菌、婴儿沙门菌、韦太夫雷登沙门菌和阿贡纳沙门菌。这些沙门菌的耐药情况严重,尤其是复方新诺明,其耐药率高达100%。Salmonella as one of the common foodborne pathogens is also one of the pathogens in causing diarrhea in weaned piglets. China is a great country in pig industry, and the economic loss due to salmonellosis in pigs is severe. The symptoms of Salmonella infection in pigs are usually typhoid, characterized by severe systemic disease, and intestinal inflammation and diarrhe- al disease. This study collected samples from pigs with diarrhea in different farms of China to investigate the prevalence and drug resistance of Salmonella. From the 128 SalmoneUa strains isolated from 571 samples from 84 farms in 16 provinces of China, we found that the most prevalent serotype was S. Typhimurium, then S. Derby, S. London, S. Infantis, S. Wehevreden and S. Ago- na. The antibiotics resistance of Salmonella isolates was severe, and all of the isolates were resistant to trimethoprim/suffamethox- azole.

关 键 词：沙门菌 分离鉴定 流行率 耐药性 猪 

分 类 号：S852.61[农业科学—基础兽医学]