高血压患者踏车试验达75%最大心率时各血压参数变化与尿微量白蛋白关系探讨  

Relationship Between Changes of Blood Pressure Parameters and Microalbuminuria in Patients With Hypertension at 75% Maximal Heart Rate on Bicycle Ergometer Exercise Test

作　　者：王世红 林璋 

机构地区：[1]福建省老年医院/福建医科大学教学医院心血管内科,福建福州350001

出　　处：《中国卫生标准管理》2017年第26期20-22,共3页China Health Standard Management

基　　金：福建省卫生计生委面向农村和城市社区推广适宜技术项目课题资助(2017009)

摘　　要：目的探讨高血压患者踏车试验达75%最大心率时各项血压指标与尿微量白蛋白(mALb)的相关性。方法纳入88例老年高血压患者,根据mALb水平分为微量白蛋白尿组(MAU组,n=30)及正常白蛋白尿组(NMAU组,n=58),测量两组运动前与踏车试验达75%最大心率时的收缩压(SBP)、舒张压(DBP),计算出平均动脉压(MAP)、脉压(PP)、运动后MAP、运动后PP、运动后与运动前MAP差值(△MAP)、运动后与运动前PP差值(△PP),分析各项指标与mALb的相关性。结果与NMAU组相比,MAU组运动后PP、运动后MAP、△PP、△MAP均升高(P<0.05)。Pearson相关分析结果显示,mALb与运动后MAP、△MAP呈正相关(P<0.05)。结论高血压患者合并mALb时,运动后MAP、运动后PP较不合并mALb升高。运动后MAP、△MAP越大,mALb风险越大。Objective To explore the relationship between changes of blood pressure parameters and microalbuminuria（mALb） in patients with hypertension at 70% maximal heart rate on bicycle ergometer exercise test（EET）.Methods A total of 88 elderly patients with hypertension were enrolled in the present study.All the patients were classified into MAU group（n=30） and NMAU group（n=58） based on the level of mALb.Systolic blood pressure（SBP）,diastolic blood pressure（DBP） of the two groups were measured before and after EET.The mean arterial pressure（MAP）,pulse pressure（PP）,exercise MAP,exercise PP,△ MAP,△ PP of the two groups were measured.The correlation between the above indexes and mALb were analyzed.Results The level of exercise PP,exercise MAP,△ PP,△ MAP in MAU group were significantly higher than that in NMAU group（P〈0.05）.Pearson correlation analysis showed that mALb was positively correlated with exercise MAP,△ MAP（P〈0.05）.Conclusion The level of exercise MAP,exercise PP in patients with hypertension complicated with mALb were significantly higher than those without mALb.The higher level of exercise MAP and △ MAP,the greater the risk of mALb in patients with hypertension.

关 键 词：老年高血压 平均动脉压 踏车试验 尿微量白蛋白 

分 类 号：R331[医药卫生—人体生理学]