冠状动脉管腔内密度衰减梯度和管腔直径衰减梯度的相关性  

Correlation between transluminal attenuation gradient and transluminal diameter gradient during CT coronary angiography

作　　者：李娇娇[1] 张斌[1] 刘迪[1] 李传贵[1] 陈静[1] 

机构地区：[1]河北北方学院附属第一医院影像科,张家口075000

出　　处：《山西医科大学学报》2017年第12期1225-1228,共4页Journal of Shanxi Medical University

基　　金：张家口市科技攻关计划资助项目(1521094D)

摘　　要：目的采用320排CT评估冠状动脉直径对冠状动脉管腔内密度衰减的影响,以及管腔内密度衰减梯度和管腔直径衰减梯度的相关性。方法采用320排CT进行CT冠状动脉造影检查。35例患者均行CT冠状动脉造影和传统X线冠状动脉造影检查。采用自动梯度软件包测量105支冠状动脉的管腔内密度衰减梯度值(transluminal attenuation gradient,TAG),同时测量105支冠状动脉的管腔直径衰减梯度值(transluminal diameter gradient,TDG)。Spearman相关分析用于评估TAG和TDG值的相关性,并采用Mann-Whitney U检验比较阴性TAG和阳性TAG的TDG的差异。结果 Spearman相关分析显示TAG和TDG间的相关性呈中度(r=0.525,P<0.001)。正常组TAG和TDG间的相关性为r=0.567,病变组TAG和TDG间的相关性为r=0.532,差异均具有统计学意义。阳性TAG的TDG值均明显高于阴性TAG(P均<0.001)。正常组和病变组的TDG值具有统计学差异(P<0.05)。结论 TAG值与TDG值间具有较好的相关性,冠状动脉直径变化是影响冠状动脉管腔内密度衰减的一种重要因素,TAG值的变化可能是TDG值变化的结果。Objective To assess the effect of coronary artery diameter on the transluminal attenuation gradient（ TAG） by 320 row computed tomography（ CT） coronary angiography,and to explore the correlation between TAG and transluminal diameter gradient（ TDG）.Methods Totally 35 patients underwent CT coronary angiography with 320 row CT scanner and invasive coronary angiography. TAGs and TDGs of 105 coronary arteries from 35 patients were measured. The correlation between TAG and TDG was performed using Spearman correlation analysis. In addition,the Mann-Whitney U test was performed for the comparison of TDG between TAG-positive and TAG-negative arteries. Results A significant correlation was found between TAG and TDG in total arteries（ r = 0. 525,P〈0. 001）. There was a significant correlation between TAG and TDG in normal group（ r = 0. 567,P〈0. 01） and lesion group（ r =0. 532,P〈0. 01）. The TDG value of positive TAG was significantly higher than that of negative TAG（ P〈0. 001）. There was significant difference in TDG values between normal group and lesion group（ P〈0. 05）. Conclusion TAG exhibits a significant correlation with TDG. The change of coronary artery diameter is an important factor affecting the attenuation of coronary artery,implying that TAG may be a secondary result of difference in diameters.

关 键 词：管腔内密度衰减梯度 管腔直径衰减梯度 CT冠状动脉造影 

分 类 号：R445[医药卫生—影像医学与核医学]