中药治疗女童乳房早发育临床观察  

Clinical Observation on Traditional Chinese Medical Treatment of Premature Thelarche Girls

作　　者：代薇[1] 王绍洁 万里鹏[1] 

机构地区：[1]大连医科大学研究生院,辽宁大连116044 [2]大连医科大学附属大连市儿童医院中医科,辽宁大连116012

出　　处：《辽宁中医杂志》2017年第11期2321-2324,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：大连市医学卫生科学研究计划(2014064)

摘　　要：目的:观察中药治疗女童乳房早发育的临床疗效。方法:将90例单纯乳房早发育女童按随机数字表法分为观察组和对照组各45例。对照组以改善饮食结构及生活习惯进行干预,观察组在此基础上以知柏地黄丸化裁治疗,3个月为1个疗程,治疗1~2个疗程,随访6~12个月。观察两组患儿治疗前后症状体征变化及不良反应情况。结果:观察组和对照组总有效率分别为88.9%和68.9%,观察组疗效优于对照组,差异有统计学意义(P<0.05);观察组中枢性性早熟转化率为2.2%,低于对照组13.3%。随访中,两组患儿均未出现明显不良反应。结论:中药治疗女童乳房早发育能够促进患儿乳房肿块消退,降低中枢性性早熟的转化率,安全有效。Objective： To observe the clinical effect of the traditional Chinese medical treatment of premature thelarche girls.Methods： Ninety premature thelarche girls were randomly divided into observation group and control group with 45 cases in each.The control group was intervened by improving their diet and lifestyle,and observation group was treated by Zhibai Dihuang Pill.The course of treatment was 3 months. Both groups were treated for 1 to 2 courses,and followed up for 6 to 12 months. The changes of symptoms and adverse reactions in both groups should be observed. Results： After treatment,the total clinical effective rates in observation group and control group were 88. 9% and 68. 9% respectively. The observation group was better than the control group,and the difference was statistically significant（ P〈0. 05）. The central precocious conversion rate of the observation group was 2. 2%,lower than the control group＇ s 13. 3%. During follow-up,there were no obvious adverse reactions in two groups.Conclusion： The traditional Chinese medical treatment of premature thelarche girls can promote the extinction of breast mass and reduce the central precocious puberty conversion rate. It is safe and effective.

关 键 词：中药治疗 乳房早发育 女童 

分 类 号：R585[医药卫生—内分泌]