Syntheses,Crystal Structures and Biological Activities of Three New Schiff Bases Derived from Substituted Salicylaldehyde and Tris Base  

作　　者：李中燕 贾国凯 袁霖 白鹏飞 何花 周勤 

机构地区：[1]Key Laboratory of Comprehensive Utilization of Advantage Plants Resources in Hunan South,Hunan University of Science and Engineering

出　　处：《Chinese Journal of Structural Chemistry》2017年第11期1797-1802,共6页结构化学（英文）

基　　金：financially supported by the Natural Science Foundation of Hunan Province(2017JJ3093);the Scientific Research Fund of Hunan Provincial Education Department(No.16B104)

摘　　要：Three new o-hydroxy Schiff bases, L1, L2 and L3, were derived from the 1：1 M condensation of substituted salicylaldehyde with tris base and were characterized by FT-IR, ^1H NMR and ^13C NMR spectroscopies. The crystal structure of L1 was also determined by single-crystal X-ray analysis, and it exists as a zwitterionic form in the solid state, with the H atom of the phenol group being transferred to the imine N atom. It adopts an E-configuration about the central C=N double bond. In addition, the biological activity assay was carried out and the results show that the Schiff-base compounds have a diverse range of biological activities against the fungi tested, which suggests great potential applications in antifungal fields in the future.Three new o-hydroxy Schiff bases, L1, L2 and L3, were derived from the 1：1 M condensation of substituted salicylaldehyde with tris base and were characterized by FT-IR, ^1H NMR and ^13C NMR spectroscopies. The crystal structure of L1 was also determined by single-crystal X-ray analysis, and it exists as a zwitterionic form in the solid state, with the H atom of the phenol group being transferred to the imine N atom. It adopts an E-configuration about the central C=N double bond. In addition, the biological activity assay was carried out and the results show that the Schiff-base compounds have a diverse range of biological activities against the fungi tested, which suggests great potential applications in antifungal fields in the future.

关 键 词：Schiff base  crystal  biological activity 

分 类 号：O641.4[理学—物理化学]