髋关节置换患者血流变及血小板活化状态对深静脉血栓发生的影响  

Influence of Hemorrheology and Platelet Activation State on Deep Venous Thrombosis Occurrence in Patients with Hip Replacement

作　　者：张晓霞[1] 李刚[1] 乔俊[1] 

机构地区：[1]广元市第一人民医院骨科,四川广元628000

出　　处：《昆明医科大学学报》2017年第12期116-119,共4页Journal of Kunming Medical University

基　　金：四川省广元市科技局临床研究基金资助项目(2016-1222-13)

摘　　要：目的观察探究髋关节置换患者血流变及血小板活化状态对深静脉血栓发生的影响.方法选取2015年7月至2017年6月期间广元市第一人民医院的30例髋关节置换术后发生深静脉血栓患者为观察组,同时期未发生深静脉血栓的30例患者为对照组.检测2组患者术后1 d、2 d及3 d的血流变及血小板活化状态指标,并比较2组的检测结果,同时采用Logistic分析上述指标与深静脉血栓发生的关系.结果观察组术后1 d、2 d及3 d的血流变及血小板活化状态指标均显著高于对照组,差异有统计学意义(P<0.05),观察组术后1 d、2 d及3 d的检测结果比较,差异无统计学意义(P>0.05),而对照组术后3 d的检测结果显著低于术后1 d及2 d,差异有统计学意义(P<0.05),Logistic分析显示,上述指标均与深静脉血栓的发生有密切的关系.结论髋关节置换患者血流变及血小板活化状态对深静脉血栓发生的影响较大,应注重对髋关节置换患者血流变及血小板活化状态的监测与改善.Objective To observe and investigate the influence of hemorrheology and platelet activation stateon deep venous thrombosis occurrence of patients with hip replacement. Methods Thirty patients with hipreplacement and deep venous thrombosis in our hospital during the time of July and June 2017 were selected as theobservation group,30 patients without deep venous thrombosis at the same time were selected as the control group.Then the hemorrheology and platelet activation indexes of two groups on 1st,2nd and 3rd day after the operation weredetected,and the detection results of two groups were compared,then the relationship between the hemorrheology,platelet activation indexes and deep venous thrombosis occurrence were analyzed by the Logistic analysis. ResultsThe hemorrheology and platelet activation indexes of observation group on 1st,2nd and 3rd day after the operationwere all significantly higher than those of control group,the differences were significant（ P〈0.05）,the detectionresults of observation group on 1st,2nd and 3rd day after the operation were compared,the differences were notsignificant（ P〉0.05 ）,while the detection results of control group on 3rd day after the operation were significantlylower than those on 1st and2nd day after the operation the differences were significant（ P〈0.05）,the Logisticanalysis showed,those indexes all had close relationship to the deep venous thrombosis occurrence. ConclusionThe influence of hemorrheology and platelet activation state for the deep venous thrombosis occurrence of patients with hip replacement are greater,and the hemorrheology and platelet activation state of patients with hip replacementshould be paid to more monitoring and improvement.

关 键 词：髋关节置换 血流变状态 血小板活化状态 深静脉血栓 

分 类 号：R654[医药卫生—外科学]