超声弹性成像和造影在慢性乙型肝炎肝纤维化评估中的效果对比  

Effect of Ultrasound Elastic Imaging and Contrast-enhanced ultrasound in the Evaluation of Hepatic Fibrosis in Patients with Chronic Hepatitis B

作　　者：吴汤娜[1] 符少清[1] 刘秉彦[1] 王东林[1] 覃伶伶[1] 

机构地区：[1]海南省人民医院超声科,海口市570311

出　　处：《实用医学杂志》2017年第23期3983-3986,共4页The Journal of Practical Medicine

基　　金：2016年海南省卫生计生行业科研项目(编号:1601320114A2008)

摘　　要：目的探讨超声弹性成像和造影在慢性乙型肝炎肝纤维化评估中的效果。方法选择2014年8月至2016年8月我院收治的慢性乙型肝炎73例为研究对象,对所有患者进行肝脏超声造影,采用目测法测量计算HAVTT1和HAVTT2,超声弹性成像测量SWV。结果随着肝纤维化程度的增加,SWV测值也随之升高,而HAVTT则逐渐缩短。HAVTT1和HAVTT2及SWV诊断肝纤维化分期的正确率分别为72.36%、76.84%及89.78%,SWV诊断正确率高于HAVTT1和HAVTT2,差异有统计学意义(P<0.05)。结论超声造影测量HAVTT1和HAVTT2可反映肝脏微循环变化,有利于区别肝硬化、纤维化及无纤维化,而测量SWV可反映肝脏的质地硬度差异,可作为判断肝纤维化程度和疗效的一种新方法。Objective To evaluate the effect of ultrasound elastography and radiography in the assessment of hepatic fibrosis in chronic hepatitis B patients. Methods Seventy patients with chronic hepatitis B were en- rolled in our hospital from August 2014 to August 2016. Liver uhrasonography was performed in all patients. HAVTT1 and HAVTT2 were measured by visual method. SWV was measured by ultrasonic elasticity imaging. Re- suits With the increase of liver fibrosis, SWV test also increased, while HAVTT gradually shortened. The correct rates of HAVTT1 and HAVTT2 and SWV in the diagnosis of liver fibrosis were 72.36%, 76.84% and 89.78%. The diagnostic accuracy of SWV was higher than that of HAVTT1 and HAVTT2, the differenee was statistically sig- nificant （P 〈 0.05）. Conclusion Aeoustic eontrast measurement of HAVTT1 and HAVTT2 ean reflect the chang- es of liver mieroeirculation, which is helpful to distinguish liver cirrhosis, fibrosis and no fibrosis. The measure- ment of SWV can reflect the difference of texture hardness of liver, which can be used as a kind of judgment on the degree and effect of hepatic fibrosis new method.

关 键 词：超声弹性成像检查 超声造影 慢性乙型肝炎 肝纤维化评估 

分 类 号：R445.1[医药卫生—影像医学与核医学] R512.62[医药卫生—诊断学] R575.2[医药卫生—临床医学]