心力衰竭的生物标记物研究进展  

Research advances in biomarkers of heart failure

作　　者：刘继轩 赵晓静[1] 贾倩[1] 孙志军[1] 刘春雷[1] 刘博罕 许振国 何昆仑[1] 

机构地区：[1]解放军总医院,北京100853

出　　处：《解放军医学院学报》2017年第12期1174-1177,共4页Academic Journal of Chinese PLA Medical School

基　　金：国家自然科学基金项目(81270272);国家高技术研究发展计划项目基金(2015AA033702)~~

摘　　要：心力衰竭是各种原因引起心脏泵血功能下降的临床综合征,反映心力衰竭病理生理的新型生物标记物,对心力衰竭的诊断、预后及治疗指导具有重要意义。本文根据生物标记物与心力衰竭不同病理生理通路的相关性进行分类,并对各生物标记物的临床应用及多生物标记物策略进行综述。Heart failure is a syndrome of cardiac pump dysfunction caused by various causes. Novel biomarkers reflecting different pathophysiological processes present in heart failure are crucially important for the diagnosis, prognosis and treatment guidance of heart failure. This article reviews the clinical applications of biomarkers based on the correlation between biomarkers and different pathophysiological pathways of heart failure, and the multiple-biomarkers strategy is also discussed.

关 键 词：心力衰竭 生物标记物 B型利钠肽 

分 类 号：R541.61[医药卫生—心血管疾病]