碳/氧化锌纳米线阵列/泡沫石墨烯电化学检测叶酸  

Electrochemical determination of folic acid using carbon/ZnO nanowire arrays/graphene foam

作　　者：王宝[1] 林轩宇[1] 黄硕 高鑫[1] 姚龙辉[1] 岳红彦[1] WANG Bao;LIN Xuan-yu;HUANG Shuo;GAO Xin;YAO Long-hui;YUE Hong-yan(School of Material Science and Engineering, Harbin University of Science and Technology, Harbin 150040, China;Department of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China)

机构地区：[1]哈尔滨理工大学材料科学与工程学院,哈尔滨150040 [2]哈尔滨医科大学附属第一医院神经内科,哈尔滨150001

出　　处：《工程科学学报》2017年第11期1647-1652,共6页Chinese Journal of Engineering

基　　金：黑龙江省自然科学基金资助项目(LC2015020);国家留学人员科技活动资助项目(2015192);哈尔滨理工大学青年拔尖创新人才培养计划资助项目(201604);黑龙江博士后科研启动基金资助项目(LBH-Q14117);哈尔滨市应用技术研究与开发资助项目(2016RAQXJ185)

摘　　要：通过化学气相沉积法制备三维(3D)泡沫石墨烯(GF),然后利用水热合成法在泡沫石墨烯表面生长氧化锌纳米线阵列(Zn O NWAs),再利用化学气相沉积法在其表面沉积碳(C),得到碳/氧化锌纳米线阵列/泡沫石墨烯(C/Zn O NWAs/GF)复合材料.用该复合材料做电极,采用电化学方法检测叶酸(FA).结果表明,三维泡沫石墨烯具有和模板泡沫镍一样的三维孔状结构,Zn O NWAs均匀且垂直地生长在泡沫石墨烯表面,碳沉积在Zn O NWAs表面.在线性范围为0~60μmol·L-1内,C/Zn O NWAs/GF电极检测FA时,灵敏度为0.13μA·μmol-1·L,且在尿酸(UA)干扰下检测FA具有良好的选择性.C/Zn O NWAs/GF电极有良好的稳定性和重复性.Three-dimensional（ 3D） graphene foam（ GF） was synthesized by chemical vapor deposition（ CVD）. Following this,ZnO nanowire arrays（ ZnO NWAs） were grown on the 3D GF by hydrothermal synthesis. Finally,carbon（ C） was deposited on the surface of ZnO NWAs by CVD to obtain a C/ZnO NWAs/GF hybrid. This composite was used to detect the presence of folic acid. The experimental results show that the GF inherits the 3D macroporous structure of nickel foam and that the ZnO NWAs are uniformly and vertically grown on the 3D GF. The length and diameter of the ZnO nanowires are ~ 50 nm and 2 μm,respectively. Carbon is deposited on the surface of ZnO NWAs,and the C/ZnO NWAs/GF is used as a working electrode to detect folic acid（ FA） using an electrochemical method. The experimental results show that the sensitivity of the electrode for FA is 0. 13 μA·μmol-1·L and it has good selectivity for detecting FA in the presence of uric acid. The electrode also has excellent reproducibility and stability.

关 键 词：泡沫石墨烯 氧化锌纳米线阵列 碳 电化学生物传感器 叶酸 尿酸 

分 类 号：TB332[一般工业技术—材料科学与工程] TP212.3[自动化与计算机技术—检测技术与自动化装置]