响应面法优化-β-环糊精诱导α-溴代萘的室温磷光测定  

Determination ofα-Bromonaphthalene with β-Cyclodextrin-induced Room Temperature Phosphorimetry Based on Response Surface Methodology

作　　者：张海容[1] 赵婷 

机构地区：[1]忻州师范学院生化分析技术研究所,材料与计算化学山西省高等学校重点实验室,山西忻州034000

出　　处：《分析科学学报》2017年第6期790-794,共5页Journal of Analytical Science

基　　金：山西省自然科学基金(No.2011011007-1);忻州师范学院重点学科建设项目(No.xk201402);山西省高等学校教学改革项目(No.2015-100)

摘　　要：建立了α-溴代萘的β-环糊精诱导室温磷光(β-CD-RTP)分析,用3因素、3水平Box-Behnken响应面法(RSM)优化了影响α-溴代萘的RTP实验条件。研究发现:β-CD的浓度、环己烷浓度以及Na_2SO_3浓度等对α-溴代萘的RTP强度均有显著影响;统计结果显示各影响因素的主效应关系为:β-CD浓度>NaSO_3浓度>环己烷用量。α-溴代萘RTP最佳发光条件为:β-CD的浓度为3.4×10^(-3) mol/L,环己烷的浓度为0.8μL/mL,Na_2SO_3的浓度为9.5×10^(-2) mol/L。优化条件下改进了α-溴代萘RTP分析特性,该方法的线性范围为8.0×10^(-5)~1.0×10^(-7) mol/L,检出限为1.4×10^(-8) mol/L。RSM法与传统的单因素实验法相比,有较宽的线性范围和较低的检出限。A β-cyclodextrin-induced room temperature phosphorimetry（β-CD-RTP） of a-bromonaphthalene was developed, and the experimental factors, such as p- amount of cyclohexane and sodium sulfite concentration were optimized with three for the determination CD concentration, the factors at three levels by Box--Behnken response surface methodology（RSM）. The results showed that the RTP intensity of β-bromonaphthalene was significantly influenced by β-CD concentration,the amounts of cyclohexane and sodium sulfite concentration. The statistical results showed that the effect of each factor was.. β-CD concentration）sodium sulfite concentration）the amount of cyclohexane. The optimal conditions for the phosphorescence of a -bromonaphthalene were as follows. 3. 4 X 10-3 mol/L of β-CD, 0. 8 L/mL of cyclohexane and 9.5 X 10 2 mol/L of sodium sulfite. The optimization for experimental conditions were obviously improved the analytical characters of a-bromonaphthalene RTP. Under the optimal condition,a -bromonaphthalene can be determined in the linear range from 8.0X 10 s to 1.0X 10 7mol/L,with a detection limit of 1.4X10-8 mol/L. Compared with the traditional single factor experiment,the method had a low detection limit and a wide linear range.

关 键 词：Α-溴代萘 响应面法 室温磷光 

分 类 号：O657.39[理学—分析化学]