麝香保心丸联合常规西药治疗冠心病PCI术后心绞痛疗效观察  

Observation of Shexiang Baoxin Pills Combined with Routine Western Medicine for Angina Pectoris of Coronary Heart Disease After PCI

作　　者：叶雷[1] 王健[2] 邹旭[3] 

机构地区：[1]深圳市宝安区人民医院,广东深圳518101 [2]深圳市宝安区中医院,广东深圳518000 [3]广东省中医院,广东广州510120

出　　处：《新中医》2017年第12期27-29,共3页New Chinese Medicine

摘　　要：目的:观察麝香保心丸联合常规西药治疗冠心病经皮冠状动脉介入(PCI)术后心绞痛的临床疗效。方法:将82例冠心病PCI术后心绞痛患者随机分为治疗组和对照组,每组41例。对照组给予冠心病二级预防西药治疗,治疗组在此基础上加用麝香保心丸。治疗后评估2组心绞痛疗效和心电图疗效,记录2组心绞痛发作次数、持续时间及硝酸甘油的使用情况。结果:治疗组心绞痛疗效总有效率90.24%,对照组心绞痛疗效总有效率70.73%,2组比较,差异有统计学意义(P<0.05)。治疗组心电图疗效总有效率78.05%,对照组心电图疗效总有效率48.78%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组心绞痛发作次数均较治疗前减少(P<0.05),心绞痛持续时间均较治疗前缩短(P<0.05);治疗组心绞痛发作次数少于对照组(P<0.05),心绞痛持续时间短于对照组(P<0.05)。治疗后,2组硝酸甘油用量均较治疗前减少(P<0.05);治疗组硝酸甘油用量少于对照组(P<0.05)。结论:麝香保心丸联合常规西药在冠心病PCI术后心绞痛患者的治疗中效果显著,可有效缓解心绞痛症状,减少硝酸甘油用量。Objective： To observe the clinical effect of Shexiang Baoxin pilrs combined with routine western medicine for angina pectoris after percutaneous coronary intervention（PCI） of patients with coronary heart disease. Methods： Divided 82 cases of patients with angina pectoris of coronary heart disease after PCI into the treatment group and the control group randomly, 41 cases in each group. Both groups were given secondary prevention of western medicine treatment for coronary heart disease, while the treatment group was additionally received Shexiang Baoxin pills. Evaluated the curative effect of angina pectoris and electrocardiogram after treatment, and recorded seizure times and duration of angina pectoris as well as application of nitroglycerin. Results： The total effective rate of curative effect of angina pectoris was 90.24% in the treatment group and was 70.73% in the control group, the difference being significant （P 〈0.05）. The total effective rate of electrocardiogram was 78.05% in the treatment group and was 48.78% in the control group, the difference being significant （P〈0.05）. After treatment, the seizure times and duration of angina pectoris in both groups were less or shorter than those before treatment（P〈 0.05）. The seizure times and duration of angina pectoris in the treatment group were less or shorter than those in the control group（P〈 0.05）. After treatment, application of nitroglycerin of both groups was reduced when compared with that before treatment（P〈 0.05）; the application of nitroglycerin in the treatment group was lower than that in the control group（P〈 0.05）. Conclusion： Shexiang Baoxin pills combined with routine western medicine has significant effect in treating angina pectoris after PCI of patients with coronary heart disease, which can effectively relieve the angina pectoris symptoms and reduce the application amount of nitroglycerin.

关 键 词：冠心病 心绞痛 冠状动脉介入(PCI) 麝香保心丸 硝酸甘油 

分 类 号：R541.4[医药卫生—心血管疾病]