中西医结合治疗寻常型痤疮临床观察  

Clinical Observation of Integrated Chinese and Western Medicine Therapy for Acne Vulgaris

作　　者：陆威[1,2] 汤怡 罗宏宾[3] 陶小华 

机构地区：[1]浙江省人民医院皮肤科,浙江杭州310014 [2]杭州医学院附属人民医院皮肤科,浙江杭州310014 [3]浙江省中医院皮肤科,浙江杭州310000

出　　处：《新中医》2017年第12期104-106,共3页New Chinese Medicine

基　　金：浙江省医药卫生科技计划项目资助(2015KYA020)

摘　　要：目的:观察中西医结合治疗寻常型痤疮的临床疗效。方法:将纳入的92例寻常型痤疮患者随机分为2组各46例。对照组口服盐酸米诺环素胶囊及外用0.025%维A酸乳膏治疗,观察组在对照组治疗方案的基础上加用中药汤剂内服,2组均治疗6周。观察2组治疗前后痤疮等级分布情况,皮疹脓疱、颜面油光、舌脉积分的变化并评估临床疗效。结果:治疗后,2组痤疮等级分布情况比较,差异有统计学意义(P<0.05)。治疗后,2组皮疹脓疱、颜面油光、舌脉积分较治疗前均降低,差异均有统计学意义(P<0.05)。观察组各项症状积分下降比对照组更明显,2组比较,差异均有统计学意义(P<0.05)。总有效率对照组86.96%,观察组97.83%,2组临床总有效率比较,差异有统计学意义(P<0.05)。结论:在口服盐酸米诺环素胶囊和外用0.025%维A酸乳膏治疗的基础上加用中药汤剂治疗寻常型痤疮,能改善痤疮皮损的严重程度,降低中医症状积分,疗效良好。Objective： To observe curative effect of integrated Chinese and western medicine therapy on acne vulgaris. Methods： Divided 92 patients with acne vulgaris into two groups, 46 cases in each group. Control group was given oral minocycline hydrochloride capsules and 0.025% tretinoin cream for external application. Observation group was given modified oral Chinese medicine decoction based on treatment of the control group. Both groups received treatment for six weeks. Observed distribution of acne grade, change in scores of pustular rash, oil-lustrous complexion and tongue pulse of both groups before and after treatment, and evaluated curative effect. Results： After treatment, compared distribution of acne grade in both groups, the difference was significant （P 〈0.05）. After treatment, scores of pustular rash, oil-lustrous complexion and tongue pulse in both groups were decreased, when compared with those before teatment; decrease of above symptom scores in observation group were more significant in comparison to that of the control group, differences being significant （P 〈0.05）. The total effective rate was 86.96% in control group and 97.83% in observation group, the difference being significant （P 〈0.05）. Conclusion： Based on the combination of minocycline hydrochloride capsules and 0.025% tretinoin cream for external application, applying modified oral Chinese medicine decoction for acne vulgaris is more effective than using western medicine only, which can reduce severity of ache, achieve obvious effect, and is worth of clinical application.

关 键 词：寻常型痤疮 湿热夹瘀证 中西医结合疗法 消痤1号 盐酸米诺环素胶囊 维A酸乳膏 

分 类 号：R758.73[医药卫生—皮肤病学与性病学]