基于Gabor小波-传递熵的脑-肌电信号同步耦合分析  

Synchronous analysis of corticomuscular coherence based on Gabor wavelet-transfer entropy

作　　者：张园园[1] 邹策 陈晓玲[1] 尹永浩 程生翠 陈迎亚[1] 谢平[1] 

机构地区：[1]燕山大学电气工程学院河北省测试计量技术与仪器重点实验室,河北秦皇岛066004

出　　处：《生物医学工程学杂志》2017年第6期850-856,共7页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(61271142;61673336);河北省自然科学基金资助项目(F2015203372)

摘　　要：人体运动中脑电(EEG)信号和肌电(EMG)信号间的同步特征能够反映皮层肌肉间功能耦合(FCMC)的关系。本文将Gabor小波和传递熵(TE)结合,提出一种新的方法(Gabor-TE)用以定量分析不同恒定握力下EEG-EMG信号间的非线性同步耦合特征及方向特性。本研究首先选取9名健康受试者在4种不同恒定握力下的EEG、EMG信号,并以Gabor小波变换进行局部分解;然后计算频带TE值并定义单位传递面积指标(ATE),分析恒定握力下EEG-EMG信号的局部频段同步特征及方向特性;最后探究EEG信号和EMG信号功率谱对Gabor-TE方法分析结果的影响。本文研究结果表明:恒定握力下,β频段EEG→EMG方向TE值高于EMG→EEG方向,且随握力水平增加EEG→EMG方向上β频段ATE值降低;γ频段TE值在EMG→EEG和EEG→EMG方向上的差异随握力增加而呈现出一定的变化规律;EMG功率谱与特征频段TE结果强相关。本文试验结果表明,Gabor-TE方法能定性、定量描述EEG-EMG信号在局部频带和信息传递上的非线性同步耦合特征,今后或可为研究运动控制及患者康复评价提供一定的理论依据。Synchronization analysis of electroencephalogram （EEG） and electromyogram （EMG） could reveal the functional corticomuscular coupling （FCMC） during the motor task in human. A novel method combining Gabor wavelet and transfer entropy （Gabor-TE） is proposed to quantitatively analyze the nonlinearly synchronous corticomuscular function coupling and direction characteristics under different steady-state force. Firstly, the Gabor wavelet transform method was used to acquire the local frequency-band signals of the EEG and EMG signals recorded from nine healthy controls simultaneously during performing grip task with four different steady-state forces. Secondly, the TE of local frequency-band was calculated and the unit area index of the transfer （ATE） was defined to quantitatively analyze the synchronous corticomuscular function coupling and direction characteristics under steady-state force. Lastly, the effect of EEG and EMG signal power spectrum on Gabor-TE analysis was explored. The results showed that the coupling strength in the beta band was stronger in EEG--＋EMG direction than in EMG--＋EEG direction, and the ATE values in the beta band in EEG--＋EMG direction decreased with the force increasing. It is also shown that the difference in TE values of gamma band present a varying regularity as the increase of force in both directions. In addition, EMG power spectrum was significantly correlated with the result of Gabor-TE inspecific frequency band. The results of our study confirmed that Gabor-TE can quantitatively describe the nonlinearly synchronous corticomuscular function coupling in both local frequency band and information transmission. The analysis of FCMC provides basic information for exploring the motor control and the evaluation of clinical rehabilitation.

关 键 词：皮层肌肉耦合 恒定握力 GABOR小波变换 传递熵 局部频带 

分 类 号：R318[医药卫生—生物医学工程] TN911.6[医药卫生—基础医学]