动物肠道菌群的研究进展  

Recent progress in the research of animal′s intestinal microflora

作　　者：李世芳[1] 赵付荣[1] 常惠芸[1,2] 张永光 

机构地区：[1]中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室国家口蹄疫参考实验室,甘肃兰州730048 [2]江苏省动物重要疫病与人兽共患病防控协同创新中心,江苏扬州225009

出　　处：《中国微生态学杂志》2017年第11期1354-1361,共8页Chinese Journal of Microecology

基　　金：牛羊重大动物疫病基因工程疫苗及防控研究(2017YFD0500902);国家生猪产业体系项目(CARS-36-06B)

摘　　要：肠道微生物是由存在于肠道部位的细菌、古菌、真菌、原生动物以及病毒所组成的群体。人们通过对细菌16SrRNA序列进行测序与分析,对动物及其在特定条件下的肠道菌群进行了相关方面的研究并取得了很大的进展。此外,由微生态原理发展而成的益生菌、益生元和合生元等微生态制剂,可维持机体肠道微生物的平衡、提高肠道屏障功能、增强机体免疫力。因此越来越多的微生态制剂应用于畜牧业、水产业中。论文综述了小鼠、犬、猪这三种动物的肠道菌群及其应用的研究进展,旨在为进一步深入了解动物肠道菌群的结构、功能以及促进微生态制剂的应用提供参考。The intestinal microflora colonized in animal′s gastrointestinal tract are consisted of bacteria,archaea,fungi,protozoa and viruses.Until now,researchers have developed a series of technologies to study the intestinal microflora in kinds of animals by sequencing and analyzing the 16 SrRNA of bacteria,and some great progress have been made in this period.What′s more,a series of microecological agents,such as probiotics,prebiotics and synbiotics,have been developed.It has been demonstrated that they could maintain the balance of intestinal microflora,improve intestinal barrier function,and enhance immunity.For this reason,more and more microecological agents have been applied in animal husbandry and aquaculture.In this article,we reviewed the progress in the research of the intestinal flora on animals,including mouse,dog and swine,as well as the applications of microecological agent,in order to provide some references for the research and application of intestinal microflora in future.

关 键 词：肠道菌群 小鼠 犬 猪 微生态制剂 

分 类 号：S852.4[农业科学—基础兽医学]