临床病例讨论——卵巢过度刺激综合征  

The diagnosis and treatment of ovarian hyperstimulation syndrome: a case report

作　　者：刘文杰 周丽颖[1] 王树玉[1] 杨晓葵[1] 张军[1] 刘英[1] 

机构地区：[1]首都医科大学附属北京妇产医院生殖医学科,100026

出　　处：《北京医学》2017年第11期1156-1159,共4页Beijing Medical Journal

基　　金：国家自然科学基金(81471520);北京市自然科学基金(5122015);北京市卫生系统高层次卫生技术人才培养项目(2014-3-075)

摘　　要：目的总结体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)治疗周期中发生卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS)的诊疗过程。方法对1例因不孕行控制性超促排卵(controlled ovarian hyperstimulation,COH)发生OHSS患者的诊断过程和治疗方法进行总结分析。结果本例不孕妇女因行COH后发生OHSS,经人血白蛋白补液治疗2 d后不见好转,行2次腹水穿刺并加大白蛋白的剂量,腹水仍有上升趋势。后出现胸水,住院观察,给予人血白蛋白补液及利尿治疗4 d,病情好转。结论对发生OHSS的高危人群,如多囊卵巢综合征(polycystic ovarian syndrome,PCOS)患者,建议及时预防OHSS的发生。对于已经发生中、重度OHSS的患者,要及时输注人血白蛋白等进行治疗,无好转者,可收住院,在密切监测下进行治疗。Objective To analyze the diagnosis and treatment of ovarian hyperstimulation syndrome （OHSS） in pa- tient with in vitro fertilization and embryo transfer （IVF-ET）. Methods A patient suffered with OHSS after controlled ovarian hyperstimulation （COH）, was described and analyzed. Results The clinical status of OHSS patient was not im- proved after two-day treatment with human serum albumin infusion. Ascites increased even though drainage of ascites was performed twice and the dose of albumin infusion was increased. Furthermore, pleural suffusion was found. The pa- tient was hospitalized to infuse human serum albumin and diuresis. After four-day treatment, the clinical condition was im- proved. Conclusion Timely precautions should be paid in high-risk patients of OHSS. For those moderate to severe OHSS patients, injection of human serum albumin should be done promptly.

关 键 词：卵巢过度刺激综合征 控制性超促排卵 体外受精 诊断 治疗 

分 类 号：R714.8[医药卫生—妇产科学]