甘爱萍治疗腹泻型肠易激综合征(肝郁脾虚证)的临床疗效观察  

Clinical observation of Gan Aiping's experiences in treatment of liver stagnation and spleen deficiency syndrome and diarrhea-predominant irritable bowel syndrome

作　　者：张萌[1] 朱光建 

机构地区：[1]湖北省中医院,湖北武汉430061 [2]湖北中医药大学中医临床学院,湖北武汉430061

出　　处：《中国中西医结合消化杂志》2017年第11期842-845,共4页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：[目的]探讨甘爱萍教授用自拟方"肠泻宁"医治腹泻型肠易激综合征(肝郁脾虚证)患者的临床疗效,从中归纳可推广的宝贵经验。[方法]依照中西医诊断标准,归避影响因素,挑选出60例试验者,随机分成治疗组和对照组,每组30例,治疗组予以"肠泻宁"辨证化裁,对照组予以匹维溴铵片口服,疗程各为1个月。继而从综合疗效、中医证候积分、治疗后三个月的复发率、安全性4个方面评价2组疗效。[结果]经数据精准分析,相比于医治前,2组医治后的综合疗效、中医证候积分均有明显变化,差异有统计学意义(P<0.05),医治后2组间对比,"肠泻宁"组较之"匹维溴铵"组疗效更为突出,差异有统计学意义(P<0.05),2组治疗后3个月复发情况比较,"肠泻宁"组明显低于"匹维溴铵"组(P<0.01)。[结论]"肠泻宁"功可疏肝健脾、渗湿止泻,方药组成精确合理,对于肠易激综合征治疗效果显著。[Objective]To investigate the clinical efficacy of Gan Aiping＇s experiential Changxiening decoction in treatment of liver stagnation and spleen deficiency syndrome of IBS-D,and sum up valued experiences.[Methods]According to the diagnostic criteria of Chinese and western medicine,60 patients were selected and divided into two 2 groups equally and randomly.The treatment group was given Changxiening decoction,and the control group was given pinaverium bromide tablets.The course of treatment was one month.Then to evaluate the efficacy based on comprehensive efficacy,score of TCM syndrome,recurrence rate of three months after treatment and safety.[Results]Two groups after treatment both had significant differences in comprehensive efficacy and score of TCM syndrome,and differences were statistical significance（P〈0.05）.The comparison of two groups showed that treatment group had better efficacy than control group,and differences were statistical significance（P〈0.05）.The treatment group had lower recurrence rate than the control group,and differences were statistical significance（P〈0.001）.[Conclusion]Changxiening decoction,which is precisely formed of certain herbs,can smooth liver and strengthen spleen,and has prominent effect on IBS-D.

关 键 词：肠易激综合征 肝郁脾虚 腹泻 肠泻宁 

分 类 号：R442.2[医药卫生—诊断学]