麝珠明目散的抗炎和耐缺氧实验研究  

Experimental study on Anti-inflammatory and Resist hypoxia Action of Shezhu Mingmu San

作　　者：吴国土[1] 王瑞幸[1] 黄自强[1] 

机构地区：[1]福建医科大学生理病生系,福州350004

出　　处：《海峡药学》2002年第4期19-20,共2页Strait Pharmaceutical Journal

摘　　要：目的 观察麝珠明目散的抗炎和耐缺氧作用。方法 本文用麝珠明目散滴眼液外涂,可明显减轻角叉菜胶引起小鼠足趾肿胀和二甲苯引起小鼠耳廓肿胀的作用。用6％麝珠明目散滴眼液口服,可明显增强小鼠的耐缺氧能力。结果 表明麝珠明目散滴眼液各剂量组与对照组比较有明显的抗炎作用和耐缺氧能力。结论 麝珠明目散具有耐缺氧及抗炎作用。OBJECTIVE To study or anti-inflammatory and resist hypoxia action of Shezhu Mingmu San. METHODS It (3%, 6%, 12%SZMMS; forexternai use; n = 10) markedly ameliorated paw edema by Carrageenin (P< 0.001) in mice. It significantly decreased swelling of mice ear (P<C 0.001) by induced dimethylbenzene. It(6%SZMMS;p. o;n = 10)markedly increased the capacity of resist hypoxia in small mouse(P <0. 001). RESULTS This study indicates that SZMMS might be a good drug for treating eyes diseases.

关 键 词：麝珠明目散 抗炎 耐缺氧 实验研究 

分 类 号：R285.5[医药卫生—中药学] R287.81[医药卫生—中医学]