机构地区:[1]西安冶金医院急诊科,710077 [2]西安高新医院老年病科 [3]陕西省核工业215医院急诊科 [4]西安雁塔祈康中西医结合医院呼吸科 [5]粤北人民医院呼吸内科
出 处:《中华保健医学杂志》2017年第6期480-482,共3页Chinese Journal of Health Care and Medicine
摘 要:目的探讨无创呼吸机对慢性阻塞性肺疾病合并呼吸衰竭患者心率、呼吸频率、血气分析的影响情况。方法选取粤北人民医院呼吸科收治的慢性阻塞性肺疾病合并呼吸衰竭患者80例,以随机数表法分为对照组和观察组各40例,对照组予常规抗感染、化痰平喘、糖皮质激素等对症治疗,1周为1个疗程,治疗4个疗程;试验组予无创呼吸机辅助患者呼吸,每天使用4~6次,每次使用1~2 h,其余治疗同对照组,1周为1个疗程,治疗4个疗程。治疗结束后,对比两组患者心率、呼吸频率、血气分析变化情况。结果治疗后两组患者心率水平明显改善,呼吸频率明显降低,且试验组心率(101.5±11.2)次/min、呼吸频率(22.1±2.6)次/min,较对照组心率(120.1±10.9)次/min、呼吸频率(29.8±2.7)次/min明显降低,差异有统计学意义(P<0.05);治疗后两组血气分析水平均不同程度恢复,且试验组血氧分压(PaO_2)(80.17±2.19)mmHg、二氧化碳分压(PaCO_2)(58.31±3.27)mmHg、血氧饱和度(SaO_2)(96.33±1.89)%较对照组PaO_2(55.33±3.01)mmHg、PaCO_2(70.22±3.98)mmHg、SaO_2(80.23±1.25)%恢复明显较好,差异具有统计学意义(P<0.05)。结论无创呼吸机能够明显改善呼吸衰竭患者心率、呼吸频率及血气分析结果,促进肺功能恢复,并提高临床疗效,具有临床应用价值,值得临床推广。Objective To investigate non-invasive ventilation in chronic obstructive pulmonary disease and respiratory failure in patients by analyzing heart rate,respiratory rate,and blood gas analysis to determine the impact of the situation. Methods A total of 80 patients with chronic obstructive pulmonary disease and respiratory failure were admitted to the respiratory department of our hospital. After being randomly assigned to groups,the 40 patients in the control group were treated with conventional antibiotics for phlegm,corticosteroids for asthma,and other symptomatic treatment;one week was considered a course of treatment,and the patients were treated for four courses. In the experimental group(40 patients),patients were treated with non-invasive ventilator-assisted breathing for 1-2 h,4-6 times a day. The rest of the treatment for the control group involved a one-week course of treatment for four courses. After the end of treatment,the two groups were analyzed and compared for changes in heart rate,respiratory rate,blood gas.Results 1) After treatment,patients exhibited significantly improved levels of heart rate;the heart rate of the experimental group(101.5 ± 11.2/min) was significantly lower than the control group(120.1 ± 10.9/min),and the difference was statistically significant(P〈0.05);2) After treatment,patients exhibited a significantly reduced respiratory rate;the respiratory rate of the experimental group(22.1 ± 2.6/min)was significantly higher than the control group(29.8 ± 2.7/min),and the difference was statistically significant(P〈0.05). 3) After treatment,the average of two different levels of blood gas and water recovery were analyzed. The experimental group's PaO_2(80.17 ± 2.19 mmHg),PaCO_2(58.31 ± 3.27 mmHg),and SaO_2(96.33 ± 1.89%) levels recovered significantly better than and the control group's PaO_2(55.33 ± 3.01 mmHg),PaCO_2(70.22 ± 3.98 mmHg),and SaO_2(80.23 ± 1.25%); the difference was statistically significant(P〈
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