上海市徐汇区2008-2015年自愿咨询检测确认艾滋病病毒阳性人群状况研究  

Study on the infection status of HIV-positive population from Shanghai Xuhui voluntary counseling and testing from 2008 to 2015

作　　者：蔡晓峰[1] 陶懂谊[1] 何晓雯[1] 张铁军 

机构地区：[1]上海市徐汇区疾病预防控制中心艾性结麻科,上海200237 [2]复旦大学公共卫生学院流行病学教研室,上海200032

出　　处：《中华疾病控制杂志》2017年第12期1263-1266,共4页Chinese Journal of Disease Control & Prevention

基　　金：社会组织参与艾滋病防治基金(2016-2017310104PYDMSM000651)

摘　　要：目的分析徐汇区2008-2015年获得性免疫缺陷综合征(简称艾滋病)(acquired immunodeficiency syndrome,AIDS)自愿咨询检测(voluntary counseling and testing,VCT)确认艾滋病病毒阳性人群的人口学特征和危险因素,比较VCT门诊和医疗机构发现的艾滋病感染者在感染途径、CD4计数和病程变化之间的差异。方法采用横断面研究,描述性分析VCT确认阳性人群相关信息。建立VCT组和医疗机构组,对两组相关数据进行回顾性分析比较。结果 VCT确认阳性者中男女比例为21.09∶1,20~29岁组占48.97%,未婚者占71.60%,大专及以上文化程度占67.49%。男男性行为人群(men who have sex with men,MSM)、<20岁组和≥50岁组人群、离异或丧偶组人群、低文化程度人群的阳性率较高。VCT组同性传播比例高于医疗机构组。两组首次CD4检测中位值分别为360个/μl和293个/μl。从感染者转变为病人的比例分别为29.63%和49.62%,发病潜伏期中位值分别为2 115 d和942 d。结论徐汇区VCT确认阳性者以年轻、未婚、高学历的MSM人群为主。青年学生、老年人、低文化程度及离异或丧偶等高危亚人群要重点关注。VCT的早发现优势高于医疗机构。Objective To analyze the social demographic characteristics and the risk factors of HIV-positive population from Xuhui voluntary counseling and testing （VCT） from 2008 to 2015, and compare the differences of infec- tious mutes, CIM counts and progression of disease between two groups of patients who were detected from VCT and general hospitals. Methods Cross-sectional study was conducted to describe the relative information of HIV-positive population from ~CT. The ~CT group and the hospital group were established and the relative data of two groups was collected for ret- rospective study and comparison. Results Among VCT-positive population, the ratio between male and female was 21.09 ： 1. 48. 97% of the patients were among the age of 20 to 29. 71.60% were unmarried, and 67.49% had the college degree or higher education level. The groups, who were men who have sex with men （MSM） , or with the age 〈20 or I〉50, or divorced and widowed, or with lower education level, had higher positive rates. The percentage of homosexual transmission in VCT group was higher than that of hospital group. The median values of the first CIM test were 360 cells/~ and 293 cells/ Ixl. The median values of incubation period were 2 115 days and 942 days. Conclusions Most of the positive patients from Xuhui VCT are young, unmarried MSM population with higher education level. Those high-risk subgroups, such as young students, elderly population, lower education level groups, divorced or widowed population, should be paid close attention. The advantage of early discovery of HIV patients from VCT is obviously higher than that of general hospital.

关 键 词：人免疫缺陷病毒 病毒潜伏期 流行病学研究 

分 类 号：R51[医药卫生—内科学] R181[医药卫生—临床医学]