胎儿肝脏21种化学元素含量的动态变化规律及其营养生理学意义  

Dynamics of contents of chemical elements in fetal liver, and its physiological and nutritional significance

作　　者：侯少范[1] 王丽珍[1] 李海蓉[1] 李德珠[1] 杨林生[1] 李崇正[2] 

机构地区：[1]中国科学院地理科学与资源研究所,北京100101 [2]北京中医药大学附属护国寺医院,北京100035

出　　处：《卫生研究》2002年第4期220-223,共4页Journal of Hygiene Research

基　　金：国家自然科学基金资助项目 (No .49971 0 0 3)

摘　　要：为探索胎儿肝脏化学元素的含量及其动态变化规律和营养生理学意义 ,通过分析 4～ 10月龄胎儿肝脏 2 1个化学元素的含量并与成人比较 ,将 2 1种元素的月平均值与胎儿月龄进行相关分析、分类。结果表明 ,胎儿生长发育过程中肝脏化学元素的含量呈不均匀的非稳定状态且随月龄而变化 ,其变化趋势可区分为与月龄增长呈显著正相关、显著负相关和相关不显著 3类。呈显著正相关元素的含量在胚胎 -胎儿 -新生儿、婴幼儿期由低向高变化 ,表明母体这些元素除供胎儿整体发育所需外 ,仍可使胎儿肝脏中的这类元素含量有所增加 ;呈显著负相关的元素由高向低变化 ,使单位组织质量中元素的含量很快减少 ,增加了组织对这类元素缺乏的敏感性 ;The dynamics of contents of chemical elements in fetal liver, and its physiological and nutritional significance are studied. Twenty-one chemical elements in livers of fetus from induced abortion aged four to ten months are measured and are compared with those in adult. The relativity between the monthly average contents of twenty-one elements and fetus month age are analyzed and assorted. The results show that the contents of chemical elements of fetus liver are not well distributed and are not stable during the stage of fetus growth, and even change following the fetus's age. The changing patterns of contents of chemical elements of fetus liver can be divided into three types: a marked positive relativity of some chemical element contents with the increase in fetus age, marked negative relativity with the increase of fetus age, and indefinite relativity with the increase of fetus age. In the time period of embryo development to fetus to newborn infant, the content of some elements that has marked positive relativity with the increase of fetus age varies from low to high, indicating an increase of their contents in liver of fetus while supplying the need of fetus growth. The content of elements that have marked negative relativity with the increase of fetus age varies also from low to high and rapidly decreases in per unit tissue, resulting in an increase of the sensitivity to deficiency of these elements. The contents of elements that have indistinctive relativity with the increase of fetus age may not bring about any impact to fetus and newborn infant from the view of physiology and nutrition.

关 键 词：胎儿 肝脏 化学元素 动态变化 营养生理学意义 

分 类 号：R714.5[医药卫生—妇产科学]