2-羟基萘-1-甲醛Cu(Ⅱ)配合物的合成、晶体结构和抗菌活性  

Synthesis,Crystal Structure and Antifungal Activities of Cu(Ⅱ) Complex Based on 2-Hydroxynaphthalene-1-carbaldehyde

作　　者：王大伟 周林宗 杨思林 何子康 史正军 WANG Da-wei;ZHOU Lin-zong;YANG Si-lin;HE Zi-kang;SHI Zheng-jun(School of Life Science;Office of Academic Affairs, Southwest Forestry University,Kunming 650224, China;School of Geographical Science and Tourism Manage- ment, Chuxiong Normal University, Chuxiong 675000, China)

机构地区：[1]西南林业大学生命科学学院教务处,云南昆明650224 [2]西南林业大学教务处,云南昆明650224 [3]楚雄师范学院地理科学与旅游管理学院,云南楚雄675000

出　　处：《化学试剂》2017年第12期1259-1262,1310,共5页Chemical Reagents

基　　金：国家自然科学基金资助项目(31260165,31560195);云南省“大学生创新创业训练”项目(201610677015)

摘　　要：在水热条件下合成了一种新的Cu(Ⅱ)配合物[Cu(nap)2],配合物的分子结构通过X-射线单晶衍射确认,并用元素分析、红外光谱、紫外光谱法对配合物进行了表征。晶体结构分析表明,配合物[Cu(nap)2]为单斜晶系,P21/c空间群,a=5.735 9(9),b=5.471 5(8),c=25.954(4),β=95.300(2)°,V=811.06(2)3,Z=2。中心Cu(Ⅱ)离子与4个氧原子采取平面正方配位构型,而且分子内所有原子均在同一个平面内,晶体中相邻两层平面的分子之间存在着边对边π…π相互作用,并以此组装成折叠层状三维超分子结构。另外,以有害稻疫真菌为对象,研究了在相同浓度下配体、金属盐及铜配合物对稻疫真菌的离体抗菌活性。结果显示,配合物[Cu(nap)2]比配体nap和Cu(OAc)2·H_2O具有更强的抑菌活性。A new Cu（Ⅱ） complex,[Cu（nap）2]was synthesized by the reaction of Cu（OAc）2·H2 O with 2-hydroxynaphthalene-1-carbaldehyde（nap） under hydrothermal conditions,and the crystal structure was determined by single crystal X-ray diffraction.Then the complex was confirmed by elemental analysis,IR and UV spectroscopy. The crystal structure shows that the complex[Cu（nap）2]crystallizes in monoclinic,P21/c space group,with a = 5. 735 9（9） ,b = 5. 471 5（8） ,c = 25. 954（4） ,β =95. 300（2） °,V = 811. 06（2） 3,Z = 2.The central Cu（Ⅱ） ion adopt square plane coordination geometry with four oxygen atoms,and all the atoms of [Cu（nap）2]molecule are in the same plane.Between the two adjacent layer π…π interactions were observed,and by which the complexes further extended into stable 3 D supramolecular framework. In addition,the title complex and ligand were screened for antifungal activities against Phytophthora fragariae fungi using the mycelial growth rate method,and complex [Cu（nap）2]shows more antifungal activity than nap and Cu（OAc）2·H2 O at the same concentration.

关 键 词：铜配合物 无机合成 单晶结构 抗菌活性 

分 类 号：O614.24[理学—无机化学]