羟基磷灰石/壳聚糖/氧化石墨烯三相复合膜合成与研究前景  

Preparation and Research Progress of Hydroxyapatite/Chitosan/Graphene Oxide Three-phase Composite Coatings

作　　者：袁秋华 陈泽汇 徐安平 张自强 巫剑波 秦草坪 张培新 

机构地区：[1]深圳大学化学与环境工程学院,广东深圳518060

出　　处：《广东化工》2017年第23期65-69,79,共6页Guangdong Chemical Industry

基　　金：国家自然科学基金资助项目(21471102);深圳市科技基础研究计划资助项目(JCYJ20150525092941007)

摘　　要：目前,基于羟基磷灰石的二相复合膜在骨修复生物材料的研究中已经取得了很大进展,其中羟基磷灰石/壳聚糖复合膜被广泛合成和应用,但仍存在力学性能不足的问题,因而限制了其在临床上的大量应用。氧化石墨烯作为新兴的材料,具备独特的层状结构并有着良好的力学性能。为了提高复合膜的强度,我们利用氧化石墨烯对羟基磷灰石/壳聚糖复合膜进行改性以进一步改善羟基磷灰石/壳聚糖复合膜的力学性能。本综述概括了羟基磷灰石/壳聚糖/氧化石墨烯复合膜的研究现状,对其特点、制备、性能进行了探究,并对基于羟基磷灰石的多相复合材料研究前景予以展望。At present, the two phase composite coatings based on hydroxyapatite have made great progress in the study of bone repair biological materials. The hydroxyapatite/chitosan composite coatings have been extensively 15.bricated and applied. But the clinical application of hydroxyapatite/chitosan composite coatings is restricted due to its insufficient mechanical properties. Graphene oxide has high mechanical strength because of their unique lametlar structure as a new-type material. In order to improve mechanical strength of the composite coatings, we attempt to utilize graphene oxide to modit~~ hydroxyapatite/chitosan composite coatings so as to enhance its performance. This review summarizes the present study of hydroxyapatite/chitosardgraphene oxide composite coatings and explores its characteristic, preparation, and relevant performance. And the development prospects of multiphase composite materials based on the hydroxyapatite are also been discussed.

关 键 词：生物复合膜 羟基磷灰石 壳聚糖 氧化石墨烯 改性方法 综述 

分 类 号：TQ174.759[化学工程—陶瓷工业]