噻唑腙2-亚环己基-1-(噻唑[4,5-b]吡啶基)肼的合成及结构表征  

Synthesis and Characterization of a Thiazole-Hydrazone Compound 2-cyclohexylidene-1-(thiazolo[4,5-b]pyridin-2-yl)hydrazine

作　　者：王晔[1] 兰红红[1] 

机构地区：[1]洛阳师范学院化学化工学院,河南洛阳471934

出　　处：《广东化工》2017年第24期29-30,共2页Guangdong Chemical Industry

摘　　要：本文从2-氨基-3-氯吡啶出发,经四步反应合成了一个含噻唑的腙类化合物2-亚环己基-1-(噻唑[4,5-b]吡啶基)肼,并通过红外及X-射线单晶衍射等表征了该化合物的结构。该化合物的晶体属单斜晶系,P2(1)/c空间群,晶胞参数:a=11.230(7)?,b=4.892(3)?,c=21.835(13)?,α=90°,β=101.931(7)°,γ=90°,V=1173.7(12)?~3,Z=4,D_c=1.394mg/m^3,R_1=0.1323。该化合物通过分子间氢键作用形成一维链状结构。In this paper, a thiazole-hydrazone compound, namely, 2-cyclohexylidene-I-（thiazolo[4,5-b]pyridin-2-yl）hydrazine, has been synthesized from 2-amino-3- chloro pyridine and characterized by IR and X-ray single crystal diffraction. The compound crystallizes in monoclinic system, space group P2（1 ）/c with a = 11.230（7） A, b = 4.892（3） A, c = 21.835（13） A, a= 90°, [3 = 101.931（7）°, y= 90°, V = 1173.7（12） A3, Z = 4, De = 1.394 mg/m3, R I = 0.1323. The molecular species are linked by intermolecular N-H...N hydrogen bonds into 1D chains.

关 键 词：噻唑-腙 合成 晶体结构 

分 类 号：TQ655[化学工程—精细化工]