病证结合动物模型研究的现状及思考  

Current Situation and Thinking of Animal Model of Disease and Syndrome

作　　者：孙艳珍 黄正团[1] 

机构地区：[1]广西中医药大学,广西南宁530001

出　　处：《中医药导报》2017年第23期8-12,共5页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：广西实验动物资源共享平台建设项目(13-29-03)

摘　　要：通过查阅文献资料,对病证结合动物模型的意义、制备方法及评价作一整体的综述,对现有的问题进行分析总结,病证结合动物模型制备的理论有2个:(1)基于"证"的概念理论的病证结合动物模型,制备方法分为2种:诱发疾病病证结合模型和自发遗传性疾病证侯模型;(2)基于西医疾病的模型叠加中医证候因素理论的病证结合动物模型,根据造模因素复合病证结合模型,制备方法也分为2种:"西医病+中医传统病因"模型和"西医病+病理生理"模型。要不断制备出更完美的模型,才有助于中西医学者更深入地研究贴近人类各种疾病的模型。Based on the literature review, the author makes a general review of the significance, prepara- tion method and evaluation of the model of syndrome differentiation, analyzes and summarizes the existing prob- lems, and studies the effective combination of disease and syndrome and the method of preparation, Evaluation question. There are two theories of disease model and animal model preparation： （1） Combined with animal mod- els, the preparation method is divided into two types： induced disease syndrome model and spontaneous heredi- tary disease syndrome model; （2） based on Western medicine model of superimposed ＇Chinese medicine syndrome factors combined with animal model animal model Factor combination model, the preparation method is divided into two types： ＂Western medicine and traditional Chinese medicine etiology＂ model and ＂Western medicine and pathophysiology＂ model. To constantly prepare a more perfect model, it will help scholars more in-depth study of various models close to human diseases.

关 键 词：病证结合 动物模型 制备 评价 

分 类 号：R285.5[医药卫生—中药学]