强直性脊柱炎合并自身免疫性甲状腺疾病的研究进展  

Review of ankylosing spondylitis with autoimmune thyroid disease

作　　者：李翊[1] 吴歆[2] 王友莲[1] 徐沪济[2] Li Yi;Wu Xin;Wang Youlian;Xu Huji(Department of Rheumatology and Immunology, Jiangxi Province People＇ s Hospital, Nanchang 330006, Chin;Department of Rheumatology and Immunology, Shanghai Changzheng Hospitals, Shanghai 200003, China)

机构地区：[1]江西省人民医院风湿免疫科,南昌330006 [2]上海长征医院风湿免疫科,200003

出　　处：《国际免疫学杂志》2017年第6期684-687,共4页International Journal of Immunology

摘　　要：强直性脊柱炎是一种常见的系统性自身免疫性疾病，除脊柱关节受累外，亦可有眼、心脏、肺等多系统受累。自身免疫性甲状腺疾病是器官特异性免疫性疾病，患者血清中可检测到高滴度的抗甲状腺抗体。某些结缔组织病如干燥综合征、系统性红斑狼疮常合并自身免疫性甲状腺疾病，但强直性脊柱炎患者甲状腺异常情况却罕见报道。因而对强直性脊柱炎合并自身免疫性甲状腺疾病的患病研究情况及发病机制进行研究有重要意义。Ankylosing spondylitis is a commen systemic autoimmune disease. Except tor spree and joints ,mutiple systems are invovled ,such as eyes ,heart and lungs. Autoimmune thyroid diseases are a group of organ-specific immune diseases characterized by the presence in serum of high-titer antibodies against thyroid. Some connective tissue diseases such as Sjogren＇ s syndrome and systemic lupus erythematosus are often accompanied with autoimmune thyroid diseases. However, thyroid disorders of ankylosing spondylitis patients are rarely reported. This article is reviewed the prevalence and pathogenesis of ankylosing spondylitis with autoimmune thyroid disease.

关 键 词：强直性脊柱炎 自身免疫性甲状腺疾病 患病率 发病机制 

分 类 号：R581[医药卫生—内分泌]