球囊扩张术与经皮腔内支架成形术治疗下肢动脉硬化闭塞的效果对比分析  

A Contrast Study of the Effect between Balloon Dilatation and PTAS in the Treatment of Low Extremity Atherosclerosis Disease

作　　者：白斗[1] 蒋岚杉[1] 武少辉 张效杰[1] 王雪钢[1] 高林 郑佳利[2] 

机构地区：[1]绵阳市中心医院血管外科,四川绵阳621000 [2]绵阳市中心医院超声科

出　　处：《西南军医》2017年第6期511-515,共5页Journal of Military Surgeon in Southwest China

摘　　要：目的探讨分析球囊扩张术与经皮腔内支架成形术治疗下肢动脉硬化闭塞的临床效果。方法将2015年3月—2016年3月我院收治的92例下肢闭塞性动脉硬化患者作为研究对象,随机分为观察组46例和对照组46例。两组患者均给予降糖、降压、抗血小板、调脂等常规治疗,对照组采用球囊扩张术,观察组采用经皮腔内支架成形术。比较两组患者临床效果,治疗前、治疗6个月踝肱指数、跛行距离及术后随访终点事件发生率。结果观察组总有效率91.3%,显著高于对照组的73.9%,差异具有统计学意义(P<0.05);治疗6个月后,观察组踝肱指数、跛行距离显著高于对照组,差异具有统计学意义(P<0.05);观察组患者术后脑出血、脑梗塞、冠心病、截肢、死亡终点事件发生率明显低于对照组(P<0.05)。结论经皮腔内支架成形术治疗下肢动脉硬化闭塞患者效果更佳,可明显改善踝肱指数、跛行距离,降低终点事件发生率,值得临床推广。Objective To compare the clinical effect of balloon dilatation with that of percutaneous transluminal angioplasty and stenting（ PTAS） in the treatment of low extremity atherosclerosis disease（ LEASD）.Methods 92 cases with LEASD hospitalized during the period from Mar.,2015 to Mar.,2016 were randomly divided into 2 groups： observation group and control group,46 in each; routine treatment of glucose-lowering treatment,antihypertensive treatment,antiplatelet treatment,blood lipid regulation and other conventional treatment were applied to cases in both groups,and balloon dilatation was performed on cases in control group while PTAS on cases in observation group; a contrast study was made between the 2 groups to the clinical effect,ankle-brachial index（ ABI） before treatment and 6 months after treatment,claudication distance and postoperative follow-up endpoint occurrence.Results The total effective rate in observation group was 91. 3%,much higher than that in control group（ 73. 9%）,the difference was of statistical significance（ P〈0. 05）; 6 months after treatment,the ABI and claudication distance of the cases in observation group were higher than those of the cases in control group,the difference was of statistical significance（ P〈0. 05）; the post-operative endpoint occurrence of cerebral hemorrhage, cerebral infarction, coronary heart disease,amputation and death in observation group was much lower than that in control group（ P〈0. 05）.Conclusions PTAS is of better effect on LEASD,it can obviously improve the ABI,claudication distance and decrease the occurrence of endpoint events; it is worthy of wider clinical application.

关 键 词：球囊扩张术 经皮腔内支架成形术 下肢动脉硬化闭塞 效果 

分 类 号：R543.5[医药卫生—心血管疾病]