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机构地区:[1]南方医科大学研究生学院,广州510515 [2]云南省玉溪市人民医院感染科,云南玉溪653100 [3]成都军区昆明总医院感染科,昆明650223
出 处:《临床肝胆病杂志》2017年第12期2416-2420,共5页Journal of Clinical Hepatology
基 金:云南省中青年学术技术带头人培养项目(第十八批)
摘 要:临床工作中经常发现肾功能异常合并HBV血清标志物阳性的患者,其中涉及多种疾病群,如肾病患者合并HBV感染(包括急性HBV感染和慢性HBV感染)及慢性HBV感染者合并肾损伤(HBV感染相关性肾炎、肝肾综合征、范可尼综合征、IFN治疗相关肾损伤)等。重点阐述在临床中如何分析肾病与HBV感染两者之间的关系,认为需提高临床医生对此类患者抗病毒治疗和如何进行监测管理的关注。Patients with abnormal renal function complicated by positive HBV serum markers are commonly seen in clinical practice,with a variety of diseases involved,such as patients with nephropathy complicated by HBV infection( including acute and chronic HBV infection)and those with chronic HBV infection complicated by renal injury( such as HBV-related nephropathy,hepatorenal syndrome,Fanconi syndrome,and renal injury induced by interferon therapy). This article elaborates on how to analyze the association between nephrology and HBV infection in clinical practice and points out that clinicians should improve the antiviral therapy for such patients and develop monitoring and management measures.
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