低频型与全频型听力损失突聋患者的内耳造影研究  

Analysis of the gadolinium-enhanced inner-ear MRI in low frequency and total frequency idiopathic sudden sensorineural hearing loss patients

作　　者：肖恒[1] 姚广南 陈曦[1] 

机构地区：[1]福建医科大学附属第一医院耳鼻咽喉研究所,福建福州350005

出　　处：《中国医学文摘（耳鼻咽喉科学）》2017年第6期299-302,共4页Chinese Medical Digest(Otorhinolaryngology)

基　　金：福建省医学创新课题(2014-CX-24)

摘　　要：目的通过内耳成像技术,比较低频型与全频型听力损失突发性聋患者的膜迷路积水阳性率,探讨内耳造影技术对突发性聋的诊断、治疗和预后评估的指导意义。方法通过鼓室内注射造影剂钆,行内耳三维快速液体衰减反转恢复核磁共振扫描,并对图像进行外淋巴间隙MRI评分,结合临床听力学资料,对低频型与全频型听力损失突发性聋的膜迷路积水相关数据进行统计学分析。结果低频型患者中,6.7%(1/15)的患者显示内耳膜迷路积水征象;对照组全频型患者中,40%(6/15)的患者显示内耳膜迷路积水征象;两组患者中钆造影比较有显著性差异(P<0.05)。结论不同频率听力损失患者的病因可能不尽相同,全频聋患者内耳膜迷路积水征象发生率也许更高。Objective To compare the positive rate of labyrinthine hydrops in patients with low-frequency and full-frequency sudden sensorineural hearing loss by Gadolinium-enhanced Inner-ear MRI,and to explore the significance of inner ear angiography in diagnosis,treatment and prognosis of sudden deafness. Methods According to the result of 3 D-FLAIR MRI after the intratympanic injection of contrast agent,and the data that including the MRI scores of the perilymphatic space together with the clinical audiologic material were analyzed statistically in low-frequency and full-frequency groups. Results In the low frequency group,6.7%（1/15）patients showed signs of endolymphatic hydrops,while in the low-frequency group,40%（6/15）patients showed signs of endolymphatic hydrops. The rates of abnormal-Gadolinium-enhanced Inner-ear MRI were significant difference（P〈0.05）between those two groups. Conclusion The pathological of hearing loss in those two groups may be different,The incidence of endolymphatic hydrops in patients with full-frequency deafness may be higher.

关 键 词：听觉丧失 感音神经性 低频型 全频型 内耳造影 

分 类 号：R764.33[医药卫生—耳鼻咽喉科]