葛根素对发热兔解热作用的实验研究  

EXPERIMENTAL STUDY OF ANTIPYRETIC EFFECT OF PUERARIN ON FEVERED RABBITS

作　　者：范书铎[1] 孙丽华[1] 梁强[1] 张晓玲[1] 

机构地区：[1]中国医科大学基础医学部生理学教研室

出　　处：《中国医科大学学报》1991年第4期250-252,256,共4页Journal of China Medical University

基　　金：国家自然科学基金

摘　　要：用整体测定家兔直肠温的方法,研究了葛根素对发热家兔的解热作用。结果表明:葛根素水溶剂静脉注射对正常体温家兔没有解热作用,但对发热家兔有明显的解热作用,而且这种解热作用与剂量相关。葛根素的解热作用不如解热药对乙酰胺基苯酚的作用强。The antipyretic effects of puerarin on fevered rabbits were investigatedwith measuring of rectal temperature in 74 unanaesthetized rabbits. The resultsshowed that no change of the normal body temperatnre was caused by puerarin. However, puerarin exerted obviously antipyretic effect on fevered rabbits. Theantipyretic effect was correlative with dose of it. The antipyretic effect ofpuerarin was wea?er than that of acetaminophen.

关 键 词：葛根素 葛根 发热 解热 

分 类 号：R282.710.5[医药卫生—中药学]