抗高血压药物的研究现状  

Status of research on antihypertensive drugs

作　　者：温改艳 袁洪[2] 舒婧娴 钟佳 陈瑞芳[2] 李莹[2] 黄利华[4] 黄志军[2] 邢晓为[4] 陆瑶[2] 

机构地区：[1]浙江医院药剂科,杭州310000 [2]中南大学湘雅三医院临床药理中心,长沙410013 [3]中南大学湘雅三医院超声科,长沙410013 [4]中南大学湘雅三医院医学实验中心,长沙410013

出　　处：《中国临床药理学杂志》2017年第24期2629-2632,共4页The Chinese Journal of Clinical Pharmacology

基　　金：国家自然科学基金面上基金资助项目(81470535);中南大学研究生自主创新课题基金资助项目(2015zzts320);中南大学博士生自主创新课题基金资助项目(2016zzts153)

摘　　要：高血压是引起心血管疾病死亡的主要危险因素,据统计全国高血压患病人数达2.7亿。目前,已经有15类,69种药物被批准用于治疗高血压,但治疗率和控制率仍然偏低。因此,有效降低顽固性高血压患者血压,减轻合并症患者靶器官损伤,并减少药物不良反应发生的新型抗高血压药物成为研究重点。本文就近些年来已上市或在研的抗高血压药物的研究现状作一综述,以期为抗高血压的研发和应用提供参考。Hypertension is the leading risk factor for death resulted from cardiovascular diseases. According to the statistics, the number of pa- tients with hypertension in China is 270 million. At present, 15 classes and 69 drugs have been approved for the treatment of hypertension, however, the treatment rate and the control rate remain low. Therefore, the research focusing on new antihypertensive drugs are how to effectively reduce the blood pressure in patients with refractory hypertension, reduce the target organ damage adverse drug reactions. in patients with complications, and reduce This paper summarized the recent research progress of anti - hypertensive drugs on the market or in development, so as to provide references for drugs. development and application of antihypertensive

关 键 词：高血压 抗高血压药物 心血管疾病 

分 类 号：R972.4[医药卫生—药品]