盐酸羟考酮在缓解剖宫产术中宫缩痛的效果观察  

Observation on the effect of oxycodone hydrochloride on reducing the uterine contractions during cesarean section

作　　者：黄少华[1] 黄丽敏 马灵 王亚娟[1] 吴艳红 

机构地区：[1]保定市妇幼保健院麻醉科,河北保定071000

出　　处：《川北医学院学报》2017年第6期877-879,共3页Journal of North Sichuan Medical College

基　　金：保定市科技局社会发展项目(17ZF085)

摘　　要：目的:对比分析盐酸羟考酮静脉注射与利多卡因硬膜外注射在缓解剖宫产术中宫缩痛的镇痛效果。方法:选取84例行剖宫产手术的产妇,按随机数表法分为两组,每组各42例。在胎儿娩出后,对照组产妇硬膜外追加利多卡因,观察组产妇静脉给予盐酸羟考酮,比较两组宫缩痛、舒适度评分量表(BCS)评分及不良反应情况。结果:观察组产妇术中宫缩痛评分(3.52±1.26)分,低于对照组的(4.53±1.32)分,差异有统计学意义(t=3.027,P=0.034);观察组产妇术毕、术后2 h、6 h、24 h的BCS评分明显高于对照组,差异有统计学意义(P<0.05);与对照组23.81%(10/42)相比较,观察组产妇的不良反应发生率7.14%(3/42)明显较低,差异有统计学意义(P<0.05)。结论:对于剖宫产产妇术中静脉给予羟考酮缓解宫缩痛的效果优于硬膜外追加利多卡因,且不良反应较少。Objective: To compare the analgesic effect of oxycodone hydrochloride intravenous injection and lidocaine epidural injection in alleviating uterine contractions in cesarean section.Methods: 84 cases of patients with cesarean section were selected as the subjects,the patients were divided into observation group and control group according to random number table method,each group of 42 cases.In the control group,patients were treated with lidocaine,and the patients in the observation group were given intravenous administration of oxycodone hydrochloride.The scores of uterine pain,comfort score scale(BCS) and adverse events were compared between the two groups of cesarean section.Results:(3.52 ± 1.26) points in the observation group were significantly lower than those in the control group(4.53 ± 1.32),the difference was statistically significant(t = 3.027,P = 0.034).The BCS score of the observation group was significantly higher than that of the control group at 6 h,12 h,24 h and 48 h after operation,the difference was statistically significant(P < 0.05).Compared with the control group(23.81%),the incidence of adverse reactions(7.14%) in the observation group was lower,the difference was statistically significant(P < 0.05).Conclusion: Compared with lidocaine epidural injection,oxycodone hydrochloride intravenous injection has more significant effect in relieving uterine contraction pain,and has less adverse reactions.

关 键 词：盐酸羟考酮 利多卡因 剖宫产术 宫缩痛 

分 类 号：R614[医药卫生—麻醉学]