子宫发育异常在不孕不育患者中发生率的单中心研究  

The Incidence of Congenital Uterine Anomalies in Infertile Women

作　　者：彭燕蓁[1] 段华[1] 郭银树[1] 成九梅[1] 叶红[1] 付凤仙[1] 

机构地区：[1]首都医科大学附属北京妇产医院妇科微创中心,北京100006

出　　处：《国际妇产科学杂志》2017年第6期655-658,共4页Journal of International Obstetrics and Gynecology

基　　金：北京市医管局临床医学发展专项(ZY201406);卫生行业科研专项(201002013)

摘　　要：目的:探讨子宫发育异常在不孕不育患者中发生率的差异。方法:选取2006年1月—2015年1月在首都医科大学附属北京妇产医院妇科微创中心门诊因"不孕症"及"自然流产史"行宫腔镜联合超声检查的2 359例患者为研究对象,观察比较在原发不孕症(920例)、继发不孕症(722例)及自然流产患者(717例)中子宫发育异常的发生率。结果:494例诊断为子宫发育异常,其中中隔子宫408例(82.59%),单角子宫34例(6.88%),双子宫5例(1.01%),双角子宫9例(1.82%),弓形子宫30例(6.07%),T形子宫8例(1.62%)。自然流产组子宫发育异常发生率[40.31%(289/717)]高于其他2组,差异有统计学意义(均P<0.05);原发不孕症组发生率[14.46%(133/920)]高于继发不孕症组[9.97%(72/722)],差异有统计学意义(P<0.05)。自然流产组中隔子宫发生率[36.26%(260/717)]高于其他2组,差异有统计学意义(均P<0.05);而原发不孕症及继发不孕症2组间差异无统计学意义。自然流产组双角子宫发生率(0.98%)高于继发不孕症组,差异有统计学意义(P<0.05),T型子宫在原发不孕症组发生率最高(0.87%)。单角子宫、弓形子宫及双子宫发生率在3组间差异无统计学意义。结论:与不孕症患者相比,子宫发育异常在自然流产患者中发生率高,特别是中隔子宫和双角子宫患者。Objective:Investigate the different incidence of congenital uterine abnormalities in infertile women.Methods:From January 2006 to January 2015, the outpatients who undergone hysteroscopy combined with ultrasound in Center of Minimally Invasive Gynecological Surgery of Beijing Obstetrics and Gynecology Hospital were studied, the incidence of congenital uterine abnormalities in primary infertile women(920), secondary infertile women(722) and women with a history of spontaneous abortion( 717) were observed and compared. Results : There were 494 cases diagnosed as congenital uterine abnormality. Among them, 408(82.59%) cases were uterine septum, 34(6.88%) cases were unicornuate uterus, 5(1.01%)cases were uterus didelphys, 9(1.82%) cases were bicornuate uterus, 30(6.07%) cases were arcuate uterus and 8 cases(1.62%)were T-shaped uterus. The incidence of congenital uterine abnormalities in spontaneous abortion group [40.31%(289/717)] was higher than that of the other 2 groups, the difference was statistically significant(P<0.05). The incidence of congenital uterine abnormalities in primary infertility group [14.46%(133/920)] was higher than that of secondary infertility group [9.97%(72/722)],the difference was statistically significant( P<0.05). The incidence of septum uterus in spontaneous abortion group [36.26%(260/717)] was higher than that of the other 2 groups, the difference was statistically significant(P<0.05), but there was no statistically significant difference in incidence of septum uterus between the primary and the secondary infertility group. The incidence of bicornuate uterus in spontaneous abortion group(0.98%) was higher than that in secondary infertility group, the difference was statistically significant( P<0.05). The incidence of T-type uterus was highest in the primary infertility group(0.87%). There was no statistically significant difference in the incidence of unicornuate uterus, arcuate uterus and didelphys uterus between 3 groups. Conclusions:Compared with infertile patients, congenital uterin

关 键 词：不育 女(雌)性 流产 自然 子宫发育异常 

分 类 号：R711.6[医药卫生—妇产科学]