基于术后髋骨CT数据重建个性化骨肌多体动力学模型及步态仿真  

Musculoskeletal multi-body dynamic simulation on patient-specific hip bone after surgery and gait simulation

作　　者：李兴 王洪福[1] 罗伟[1] 成博[1] 王俊元[1] 刘峰[1] 

机构地区：[1]中北大学机械与动力工程学院,山西省太原市030000

出　　处：《中国组织工程研究》2017年第35期5685-5690,共6页Chinese Journal of Tissue Engineering Research

基　　金：国家自然科学基金(21604074)~~

摘　　要：背景:髋骨体内受力复杂,需要更高效、准确的方法进行有限元分析。目的:构建与患者术后髋骨相对应的个性化骨肌多体动力学模型并进行步态仿真,探究患者术后髋骨的生物力学行为。方法:根据患者术后髋骨CT数据,在MIMICS中进行三维重建,在Geomagic Studio完成实体化和位置匹配并在Hypermesh中网格化。利用Any Body软件建立患者个性化骨肌多体动力学模型,模拟正常人平地行走时的动作,导出髋骨在整个运动过程中受到的肌肉力、关节力和关节力矩,将导出的数据作为有限元分析的边界条件,在软件Abauqus上计算步态过程中髋骨受到的应力、应变的大小及其集中部位。结果与结论:(1)关节力在2.1 s时,髋关节3个方向关节力的最大值分别为600,2 000,100 N;(2)髂骨关节几乎只有在Y方向受力,最大值为1 000 N;(3)髋关节所受最大应力在30%步态周期处约为12 MPa,最大相对位移为0.5 mm;(4)结果表明,患者术后髋骨所受应力较大的部位主要集中在骶髂关节附近、髋臼后上方、髂骨中央、耻骨上方,术后髋骨所受应力较正常髋骨偏大,患者在康复过程中应注意活动强度。BACKGROUND：The biomechanical properties of the hip bone are complex in vivo that requires a more efficient and accurate method for the finite element analysis. OBJECTIVE： To develop a musculoskeletal multi-body dynamic model of the patient-specific hip joint after surgery and simulate gait, and to explore the biomechanics of the hip joint. METHODS： CT data of the patient＆#39;s hip joint postoperatively were collected, three-dimension reconstruction underwent in MIMICS, and materialization and position matched on Geomagic Studio and meshed on Hypermesh. A musculoskeletal multi-body dynamic model of the patient-specific hip joint was established using AnyBody software and simulated the normal movements during walking, then export the muscle force, oint forces, joint moment as the Boundary conditions in finite element analysis. Then, the muscle forces, joint forces and torque were obtained and imported to be the boundary conditions for finite element analysis. The stress and strain values and concentration parts were measured on Abauqus during walking. RESULTS AND CONCLUSION： （1） The maximum value of the joint force in the three directions of the hip joint was 600, 2 000, 100 N at 2.1 seconds. （2） The ilium force was almost only in the Y direction, and the maximum value was 1 000 N. （3） The maximum stress on the hip joint was about 12 MPa at 30% of the gait cycle and the maximum relative displacement was 0.5 mm. （4） To conclude, the stress of the hip after surgery is mainly concentrated on the vicinity of the sacroiliac joint, postersuperior of the acetabulum, middle region of iliac bone, and upper zone of pubic bone; the stress of the hip is higher than that of the normal hip, and the activity intensity should be paid attention during rehabilitation.

关 键 词：骨科植入物 数字化骨科 髋骨 有限元 骨肌多体动力学 步态周期 国家自然科学基金 

分 类 号：R318[医药卫生—生物医学工程]