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作 者:邹芬芳[1] 高红梅[1] 张健鹏[1] 焦宏彬[1]
出 处:《武警医学》2017年第11期1121-1123,共3页Medical Journal of the Chinese People's Armed Police Force
摘 要:目的观察百令胶囊联合桉柠蒎肠溶胶囊治疗慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)稳定期患者的临床疗效。方法将80例COPD稳定期患者随机分为研究组与对照组,每组40例,对照组常规使用布地奈德/福莫特罗粉吸入剂(信必可都保)吸入,研究组加服百令胶囊联合桉柠蒎肠溶胶囊,比较治疗6个月后两组的肺功能、运动耐力指标和急性发作次数。结果研究组治疗6个月后的FEV1/FVC为(62.6±7.6)%、6-MWD为(355.5±8.6)、6个月内急性发作次数为1.26±0.25,均优于对照组,差异均具有统计学意义(P<0.05)。结论百令胶囊联合桉柠蒎肠溶胶囊治疗慢性阻塞性肺疾病疗效显著,对改善肺功能、提高运动耐力、减少急性发作的次数等方面效果明显。Objective To investigate the therapeutic effect of Bailing capsules combined with eucalyptus lemon pinene enteric soft capsules on pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Methods A total of 80 COPD patients admitted to our hospital between January 2013 and May 2014 were selected as subjects in this study. They were randomly di- vided into two groups. One group of patients was given Budesonide and Formoterol Fumarate powder plus regular COPD treatment ( con- ventional treatment group, n = 40) , while the other group was given eucalyptus lemon pinene enteric soft capsules and Bailing capsules combined with conventional therapy (combined treatment group, n = 40). The pulmonary function, including forced expiratory volume in one second (FEV1) and forced vital capacity rate of one second (FEV1/FVC) , was tested in both groups of patients. The exercise capacity index and acute outbreak of COPD was recorded after six-month treatment. ResuhsCompared with the conventional treatment group, the combined treatment group had significantly improved lung function and exercise capacity index ( 355.5 ± 8.6 ), as was shown by elevated FEV1/FVC ( 62.6 ± 7.6 ) %, and decreased times of acute outbreak ( 1.26 ± 0.25 ) ( P 〈 0.05 ). Conclusions The effect of Bailing capsules combined with eucalyptus lemon pinene enteric soft capsules on pulmonary function in patients with COPD is significant.
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