烟、酒致骨质疏松症的实验研究进展  

Experimental study progress of smoking-and alcohol-induced osteoporosis

作　　者：李晓莉[1] 沙南南 陈楠 王拥军[2] 张岩[2] LI Xiaoli;SHA Nannan;CHEN Nan;WANG Yongjun;ZHANG Yan(School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China;Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China)

机构地区：[1]上海理工大学医疗器械与食品学院,上海200093 [2]上海中医药大学附属龙华医院,上海200032

出　　处：《中国临床药理学与治疗学》2017年第11期1299-1303,共5页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：国家中医临床研究基地龙医创新团队资助(LYCX-01);上海市自然科学基金(17ZR1430800)

摘　　要：生活方式与骨质疏松症的发生密切相关。吸烟、酗酒都是骨质疏松症发病的高风险因素。本文分别从生物模型、动物实验、细胞实验、分子机制等方面综述吸烟性骨质疏松症、酒精性骨质疏松症的最新研究进展。Life style closely correlates with the occurrence of osteoporosis.Both smoking and drinking are high risk factors for osteoporosis.This review summarized the updated research progress on biological models,animal and cell experiments,and molecular mechanisms for smoking-and alcohol-induced osteoporosis.

关 键 词：吸烟 酒精 骨质疏松 

分 类 号：R681[医药卫生—骨科学]