酰胺型非卟啉类N4配体的合成及其促进溴化铜催化的苄醇氧化性能研究  

Synthesis of amido-type non-heme N4 ligands and their application to promote CuBr_2-catalyzed benzyl alcohols oxidation

作　　者：孙斌[1] 李忆雪 SUN Bin;Li Yi-xce(Chongqing Technology and Bcsiness University,Chongqing Key Laboratory of Catalysis and Functional Organic Molecules,Chongqing 400067,Chin)

机构地区：[1]重庆工商大学催化与功能有机分子重庆市重点实验室,重庆400067

出　　处：《化学研究与应用》2017年第12期1845-1850,共6页Chemical Research and Application

基　　金：重庆工商大学重点项目(1352002)资助

摘　　要：本文报道两种未见文献报道的酰胺型非卟啉N4配体N,N’-双(3-甲基-2-氨基-苯甲酰基)乙二胺、N,N’-双(3-甲基-2-氨基-苯甲酰基)1,3-丙二胺的合成。并将这两种配体应用于CuBr_2-TEMPO体系催化氧化苄醇生成相应的醛的反应中,发现它们都能有效促进CuBr_2-TEMPO催化苯甲醇氧化成苯甲醛。并在反应最佳条件下,考察了N,N’-(3-甲基-2-氨基-苯甲酰基)乙二胺促进CuBr_2-TEMPO催化一系列苄醇氧化成相应的醛的反应,并得到了中等到好的收率。The synthesis of two amido-based non-heme N4 ligands N,N '-bis(3-methyl-2-amino-benzoyl)ethylenediamine and N,N'-bis(3-methyl-2-amino-benzoyl)1,3-propylenediamine were reported.These two ligands were used in the catalytic system of CuBr_2-TEMPO for catalytic oxidation of benzyl alcohols.The results showed that the synthesized ligands could efficiently promote CuBr_2-TEMPO-catalyzed oxidation of benzyl alcohol to corresponding aldehyde.Under the optimal reaction condition,the performances of N,N'-bis(3-methyl-2-amino-benzoyl)ethylenediamine to promot CuBr_2-TEMPO-catalyzed oxidation of a serials of benzyl alcohols were investigated and obtained moderate to good yields.

关 键 词：合成 酰胺型配体 苄醇 催化氧化 

分 类 号：O621.3[理学—有机化学]