急性缺血性中风病痰热腑实证证候要素与血栓弹力图的相关性分析  

Correlation Analysis of Symptom Elements and Signs of Terombelastogram in Acute Ischemic Stroke Patients with Phlegm-heat and Bowel-qi-obstructed Syndrome

作　　者：吴爽[1] 陈沛[1] 江澜[1] 耿花蕾 王雅惠 吕迪阳 邹忆怀[1] 

机构地区：[1]北京中医药大学东直门医院,北京100700

出　　处：《中西医结合心脑血管病杂志》2017年第23期2966-2968,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：国家"十二五"科技支撑计划项目(No.2013BAI13B022)

摘　　要：目的分析急性缺血性中风病痰热腑实证证候要素与血栓弹力图的相关性,探讨病人血液高凝状态的证候特征。方法筛选符合标准的急性缺血性中风痰热腑实证病人51例,对其证候要素进行评分,并应用血栓弹力图仪检测血液。结果入选病人证候要素表现为内火51例(100.0%)、痰湿51例(100.0%)、内风30例(58.8%)、血瘀28例(54.9%)、气虚21例(41.1%)、阴虚26例(51.0%)。入选病人血栓弹力图检测与参考范围比较,R值减小,α角、MA值增大;病人内火证候要素与血栓弹力图R值、K值呈显著负相关,与α角、CI值呈显著正相关;气虚证候要素与R值呈显著负相关,与CI值呈显著负相关;内风、痰湿、血瘀、阴虚则与血栓弹力图参数未见相关性。结论急性缺血性中风病痰热腑实证病人血液处于高凝状态,内火程度越重,对病人血液高凝状态形成作用越明显,气虚程度越重,凝血反应时间越短,凝血综合指数越高。Objective To study the characteristics of the blood hypercoagulability in acute ischemic stroke （ AIS）patients with phlegmheat and bowel qi obstructed syndrome and the link between syndromes and terombelastogram （ TEG） .Methods Fifty one AISpatients with phlegm heat and bowel qi obstructed syndrome were enrolled in this study, of which the stroke syndrome factorsscales and signs of TEG were recorded. Results There were six syndrome elements in 51 cases.There were 51 internal fire（ 100.0%） ,51 phlegm dampness（ 100.0%） , 30 internal wind（ 58.8%） , 28 blood stasis（ 54.9%） , 21 qi deficiency（ 41.1%） , 26 yin deficiency（ 51.0%） .Compared with the reference range, the value of R decreased and the values ofαand MA increased in TEG.There was asignificant negative correlation between internal fire and the value of R and K in TEG.There was a significant positive correlation be -tween qi deficiency and R value, but negatively correlated with CI value.There was no correlation between internal wind, phlegmdampness, blood stasis, yin deficiency,and TEG.Conclusion It is confirmed that the state of blood is hypercoagulable in AIS pa -tients with phlegm heat and bowel qi obstructed syndrome.The more severe the internal fire, the more significant effect on the hy -percoagulable state of the patient.The more severe the qi deficiency, the shorter coagulation time, the higher the coagulation index.

关 键 词：急性缺血性中风 脑梗死 痰热腑实证 相关性 血栓弹力图 证候要素 

分 类 号：R277.7[医药卫生—中医学]