盐酸氨溴索联合头孢哌酮钠舒巴坦钠治疗老年糖尿病合并肺炎的疗效观察  

Observation on Efficacy of Ambroxol Hydrochloride Combined with Cefoperazone Sodium and Sulbactam Sodium in Treatment of Elderly Diabetes Mellitus Complicated with Pneumonia

作　　者：张丽艳[1] 崔跃[1] 

机构地区：[1]沈阳市第五人民医院呼吸内科,辽宁沈阳110023

出　　处：《中国医院用药评价与分析》2017年第11期1506-1508,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:探讨盐酸氨溴索联合头孢哌酮钠舒巴坦钠治疗老年糖尿病合并肺炎的疗效。方法:选取2015年1月—2016年6月沈阳市第五人民医院收治的老年糖尿病合并肺炎患者80例,以随机数字表法分为观察组和对照组,每组40例。对照组患者给予盐酸溴己新片联合注射用头孢哌酮钠舒巴坦钠治疗,观察组患者给予注射用盐酸氨溴索联合注射用头孢哌酮钠舒巴坦钠治疗。采用健康调查量表评估两组患者的精神状况、社会功能、躯体功能和总体健康程度,比较两组患者临床症状消失时间、住院时间和临床疗效的差异。结果:治疗后,观察组患者精神状况、社会功能、躯体功能和总体健康评分明显高于对照组,差异均有统计学意义(P<0.05);观察组患者退热时间,咳嗽、咳痰及湿性啰音消失时间和住院时间均明显短于对照组,差异均有统计学意义(P<0.05);观察组患者的总有效率为95.0%(38/40),明显高于对照组的67.5%(27/40),差异有统计学意义(P<0.05)。结论:盐酸氨溴索联合头孢哌酮钠舒巴坦钠治疗老年糖尿病合并肺炎的疗效显著,能有效改善患者健康状况,缩短临床症状消失时间和住院时间。OBJECTIVE： To probe into the efficacy of ambroxol hydrochloride combined with cefoperazone sodium and sulbactam sodium in treatment of elderly diabetes mellitus complicated with pneumonia. METHODS： 80 patients with elderly diabetes mellitus complicated with pneumonia admitted into Shenyang Fifth People＇s Hospital from Jan. 2015 to Jun. 2016 were selected and divided into observation group and control group via random number table,with 40 cases in each. The control group was given Bromhexine hydrochloride tablets combined with cefoperazone sodium and sulbactam sodium for injection,while the observation group was given ambroxol hydrochloride for injection combined with cefoperazone sodium and sulbactam sodium for injection. Health survey scale were adopted to assess the mental states,social functions,physical functions and general health conditions of two groups,the disappearance time of clinical symptoms,hospital stays and clinical efficacy of two groups were compared. RESULTS： After treatment,scores of mental state,social function,physical function and general health condition of observation group were significantly higher than those of control group,with statistically significant differences（ P〈0. 05）; the disappearance time of fever,cough,expectoration,moist rale and hospital stays of observation group were significantly shorter than those of control group,with statistically significant differences（ P〈0. 05）; the total effective rate of observation group（ 95. 0%,38/40） was significantly higher than that of the control group（ 67. 5%,27/40）,with statistically significant difference（ P〈0. 05）.CONCLUSIONS： The efficacy of ambroxol hydrochloride combined with cefoperazone sodium and sulbactam sodium in treatment of elderly diabetes mellitus complicated with pneumonia is remarkable,which can significantly improve patients＇ health conditions,shorten hospital stays and disappearance time of clinical symptoms.

关 键 词：盐酸氨溴索 盐酸溴己新片 注射用头孢哌酮钠舒巴坦钠 老年糖尿病合并肺炎 

分 类 号：R974.1[医药卫生—药品]