米力农治疗小儿先天性心脏病合并重症肺炎及心力衰竭临床观察  

Clinical observation of milrinone in treatment of children with congenital heart disease complicated with severe pneumonia and heart failure

作　　者：黄海霞 

机构地区：[1]重庆儿童医院重症医学科,400014

出　　处：《中国实用医药》2017年第36期92-94,共3页China Practical Medicine

摘　　要：目的探讨米力农治疗小儿先天性心脏病合并重症肺炎及心力衰竭的临床效果。方法 110例小儿先天性心脏病合并重症肺炎及心力衰竭患儿,依据数字表法分为西地兰组与米力农组,各55例。两组均采用吸氧、抗感染等常规治疗,在此基础上西地兰组给予西地兰治疗,米力农组给予米力农治疗。比较两组病情控制效果;干预前后患儿血气分析指标、呼吸频率和心率水平;呼吸恢复平稳时间、心率恢复平稳时间、啰音消失时间、肝脏缩小时间。结果米力农组病情控制总有效率96.36%高于西地兰组的76.36%,差异具有统计学意义(P<0.05)。干预前两组血气分析指标、呼吸频率和心率水平比较差异均无统计学意义(P>0.05);干预后米力农组血气分析指标、呼吸频率和心率水平均优于西地兰组,差异均具有统计学意义(P<0.05)。米力农组呼吸恢复平稳时间、心率恢复平稳时间、啰音消失时间、肝脏缩小时间均短于西地兰组,差异均具有统计学意义(P<0.05)。结论米力农治疗小儿先天性心脏病合并重症肺炎及心力衰竭效果确切,可有效消除临床症状,改善生命体征,改善血气、呼吸频率和心率,对预后有益,值得推广。Objective To discuss the clinical effect of milrinone in treatment of children with congenital heart disease complicated with severe pneumonia and heart failure. Methods A total of 110 children with congenital heart disease complicated with severe pneumonia and heart failure were divided by number table method into cedilanid group and milrinone group, with 55 cases in each group. Both groups received conventional oxygen therapy, anti infection treatment, and cedilanid group also received cedilanid for treatment. Milrinone group received milrinone for treatment. Comparison were made on disease control effect, blood gas analysis indicators, respiratory rate and heart rate before and after intervention before and after intervention; respiratory smooth recovery time, heart rate recovery stable time, rales disappearance time, liver shrinking time between two groups. Results Milrinone group had higher total effective rate of disease control as 96.36% than 76.36% in cedilanid group, and the difference was statistically significant(P<0.05). Before intervention, both groups had no statistically significant difference in blood gas analysis index, respiratory rate and heart rate(P>0.05). After intervention, milrinone group had better blood gas analysis index, respiratory rate and heart rate than cedilanid group, and their difference was statistically significant(P<0.05). Milrinone group had shorter respiratory smooth recovery time, heart rate recovery stable time, rales disappearance time, liver shrinking time than cedilanid group, and their difference was statistically significant(P<0.05). Conclusion Milrinone shows affirmative effect in treating children with congenital heart disease complicated with severe pneumonia and heart failure, and can effectively eliminate clinical symptoms, improve vital signs, improve blood gas, respiratory rate and heart rate. It is good for the prognosis, and is worth promoting.

关 键 词：米力农 先天性心脏病 重症肺炎 心力衰竭 小儿 临床效果 

分 类 号：R725[医药卫生—儿科]